本文選題：多元共軛不飽和脂肪酸有機薄膜　切入點：納米銀單質(zhì)及CLn-Ag有機涂層　出處：《河南師范大學》2014年碩士論文

【摘要】：本論文中，我們在之前成功合成石榴酸的基礎上，通過揮發(fā)的方法在玻璃片上制備出了石榴酸——碳鏈長度為十八，含有一個共軛三烯（9順,11反,13順）的長鏈脂肪酸（CLn）的有機薄膜。此外，通過在CLn有機薄膜表面吸附具有抑菌性的納米銀、納米氧化鋅和納米氧化鎂，制備出表面修飾的CLn-Ag、CLn-MgO和CLn-ZnO有機涂層并對其抑菌作用進行評價。主要開展研究的工作包括以下幾個方面： （1） CLn有機薄膜的制備及其表征，對其抑菌性進行測試。CLn有機薄膜無論是對大腸桿菌還是金黃色葡萄球菌均顯示出良好的抑菌性。 （2）納米銀在CLn有機薄膜表面的附著，所得CLn-Ag有機涂層的性質(zhì)表征及其抑菌性的測試。掃描電鏡，高倍透鏡，XRD及能譜結(jié)果均證明附著在有機薄膜上的顆粒物為納米銀顆粒。在分別對大腸桿菌和金黃色葡萄球菌的抑菌試驗中，CLn有機薄膜與附著上的銀納米顆粒均顯示出一定的協(xié)同作用。這一性質(zhì)將促使CLn-Ag有機涂層作為生物材料應用于組織工程。 （3）納米氧化鎂的制備及其在CLn有機薄膜表面的附著，所得CLn-MgO有機涂層的性質(zhì)表征及其抑菌性測試。表征結(jié)果顯示附著在CLn有機薄膜上的顆粒物為氧化鎂納米顆粒，，但對大腸桿菌及金黃色葡萄球菌的抑菌試驗中，附著的氧化鎂納米顆粒抑制了CLn有機薄膜的抑菌性，同時，氧化鎂納米顆粒本身的抑菌活性也沒有顯示。 （4）納米氧化鋅的制備及其在CLn有機薄膜表面的附著，所得CLn-ZnO有機涂層的性質(zhì)表征及其抑菌性測試。表征結(jié)果顯示附著在CLn有機薄膜上的顆粒物為氧化鋅納米顆粒，但對大腸桿菌及金黃色葡萄球菌的抑菌試驗中，氧化鋅納米顆粒與CLn有機薄膜在抑菌性方面，對大腸桿菌有拮抗作用，對金黃色葡萄球菌有協(xié)同作用。
[Abstract]:In this paper, on the basis of the successful synthesis of pomegranate, we prepared pomegranate on glass by volatilization method. The length of pomegranate-carbon chain is 18. Organic thin films containing a conjugated triene 9, cis 11, reverse 13 cis).; in addition, by adsorbing bacteriostasis nano silver, nanometer zinc oxide and nano magnesium oxide on the surface of the CLn organic film, The surface modified CLn-ZnO and CLn-MgO organic coatings were prepared and their bacteriostatic effects were evaluated. 1) preparation and characterization of CLn organic films. The bacteriostatic properties of CLn organic films were tested. Both Escherichia coli and Staphylococcus aureus showed good bacteriostasis. (2) the adhesion of nano-silver on the surface of CLn organic film, the characterization of the properties of the obtained CLn-Ag organic coating and the test of its bacteriostasis. The results of X-ray diffraction (XRD) and energy dispersive spectrum (EDS) of high power lens show that the particles attached to the organic film are silver nanoparticles. In the bacteriostasis test of Escherichia coli and Staphylococcus aureus respectively, the silver nanoparticles attached to the organic film and the CLn film are the same. This property will promote the application of CLn-Ag organic coatings as biomaterials in tissue engineering. (3) preparation of nano-MgO and its adhesion on the surface of CLn organic film, characterization and bacteriostatic test of the obtained CLn-MgO organic coating. The characterization results showed that the particles attached to the CLn organic film were magnesium oxide nanoparticles. However, in the bacteriostatic test of Escherichia coli and Staphylococcus aureus, the bacteriostasis of CLn organic film was inhibited by the attached magnesium oxide nanoparticles, and the bacteriostatic activity of magnesium oxide nanoparticles itself was not shown. (4) preparation of nano-ZnO and its adhesion on the surface of CLn organic film, characterization and bacteriostatic test of the obtained CLn-ZnO organic coating. The characterization results showed that the particles attached to CLn organic film were ZnO nanoparticles. However, in the bacteriostatic test of Escherichia coli and Staphylococcus aureus, zinc oxide nanoparticles and CLn film had antagonistic effect on Escherichia coli and synergistic effect on Staphylococcus aureus.
【學位授予單位】：河南師范大學
【學位級別】：碩士
【學位授予年份】：2014
【分類號】：R96;O647

【參考文獻】

相關期刊論文 前1條

1 毛天球;組織工程學的昨天、今天和明天[J];第四軍醫(yī)大學學報;1999年03期

本文編號：1699527