本文選題：鋁鎂加　切入點(diǎn)：鈉含量　出處：《中國(guó)醫(yī)院藥學(xué)雜志》2017年08期

【摘要】：目的:為合成符合8.0版《歐洲藥典》標(biāo)準(zhǔn)的"鋁鎂加",采用熱水洗滌法降低"鋁鎂加"原料氫氧化鋁和氫氧化鎂中的鈉含量。方法:采用單因素試驗(yàn)考察洗滌溫度、洗滌時(shí)間、洗滌次數(shù)以及單次水量,采用原子吸收光譜法測(cè)定氫氧化鋁和氫氧化鎂中可溶鈉含量。結(jié)果:最佳洗滌工藝為,洗滌溫度80℃,洗滌時(shí)間10 min,洗滌3次,每次10倍量純化水,可將氫氧化鋁與氫氧化鎂中鈉含量降低至150 ppm以下。結(jié)論:該方法可降低"鋁鎂加"原料氫氧化鋁和氫氧化鎂中可溶性鈉含量,工藝簡(jiǎn)單,易行,確保"鋁鎂加"合成后的鈉含量符合8.0版《歐洲藥典》的質(zhì)量標(biāo)準(zhǔn)。
[Abstract]:Objective: to synthesize "aluminum-magnesium addition" which meets the standard of "European Pharmacopoeia" 8.0, and to reduce the content of sodium in aluminium hydroxide and magnesium hydroxide by hot water washing method. Methods: single factor test was used to investigate the washing temperature and washing time. The content of soluble sodium in aluminum hydroxide and magnesium hydroxide was determined by atomic absorption spectrometry. Results: the optimum washing conditions were as follows: washing temperature 80 鈩，

本文編號(hào)：1688031