本文關(guān)鍵詞： 紅蕓豆 植物凝集素 殺微生物劑 小鼠 陰道上皮細(xì)胞 切片　出處：《中國(guó)計(jì)劃生育學(xué)雜志》2016年11期 　論文類型：期刊論文

【摘要】：目的:觀察長(zhǎng)期陰道使用紅蕓豆植物凝集素(RKBL)對(duì)小鼠陰道上皮細(xì)胞的影響。方法:使用不同濃度的RKBL注入小鼠陰道連續(xù)給藥4個(gè)月后斷頸處死小鼠,取其陰道及周圍組織,制作石蠟切片并經(jīng)蘇木精染色,顯微鏡下觀察陰道組織的形態(tài)學(xué)變化。結(jié)果:小鼠陰道在濃度≤2.5mg/只的RKBL處理后,無(wú)炎癥病變,陰道粘膜上皮細(xì)胞形態(tài)完好無(wú)破損,皮下組織形態(tài)正常。而當(dāng)給藥濃度提高到5mg/只時(shí),陰道黏膜淺層上皮細(xì)胞出現(xiàn)空泡化。結(jié)論:濃度≤2.5mg/只的RKBL長(zhǎng)期使用不會(huì)引起陰道黏膜上皮細(xì)胞及皮下組織的不良反應(yīng)。
[Abstract]:Objective: to observe the effect of long-term vaginal administration of RKBLs on the vaginal epithelial cells of mice. Methods: the mice were sacrificed by vaginal administration of different concentrations of RKBL for 4 months, and their vagina and surrounding tissues were taken. The morphological changes of vagina tissue were observed under microscope. Results: after treated with RKBL with concentration 鈮，

本文編號(hào)：1525955