精神藥物對駕駛能力影響的研究進(jìn)展
發(fā)布時(shí)間:2018-01-16 06:06
本文關(guān)鍵詞:精神藥物對駕駛能力影響的研究進(jìn)展 出處:《中國藥房》2017年23期 論文類型:期刊論文
更多相關(guān)文章: 精神藥物 駕駛能力 苯二氮類藥物 抗抑郁藥 阿片類 抗癲癇藥
【摘要】:目的:了解精神藥物對駕駛能力影響的研究進(jìn)展。方法:查閱近年來國內(nèi)外相關(guān)文獻(xiàn),就精神藥物對駕駛能力影響的研究進(jìn)行歸納和總結(jié)。結(jié)果與結(jié)論:大部分精神藥物具有損害駕駛能力的作用。地西泮、氟硝西泮、勞拉西泮、替馬西泮和三唑侖等苯二氮類藥物對服用者的視覺、聽覺、注意力、緊急制動、反應(yīng)能力和手眼協(xié)調(diào)能力的損害作用明顯;唑吡坦、扎來普隆和佐匹克隆等新型非苯二氮類催眠藥容易導(dǎo)致服用者心理運(yùn)動能力和神經(jīng)心理能力測試成績的下降;阿米替林、丙咪嗪和多塞平等抗抑郁藥物可引發(fā)服用者的橫向位置保持、視覺、反應(yīng)、警惕和容忍能力的明顯損害;苯海拉明、羥嗪、咪唑斯汀和右氯苯那敏等抗組胺類藥物能顯著增加服用者駕駛過程中的橫向位置標(biāo)準(zhǔn)差和速度偏差;可待因等阿片類藥物對服用者的選擇反應(yīng)時(shí)和嗜睡的影響突出;卡馬西平和奧卡西平等抗癲癇藥物可降低服用者的車道保持能力和主觀評價(jià),增加駕駛錯誤和嗜睡。
[Abstract]:Objective: to understand the research progress of the influence of psychotropic drugs on driving ability. Methods: to review the relevant literature at home and abroad in recent years. Results and conclusions: most psychotropic drugs have the effect of impairing driving ability. Diazepam, flunitazepam, lorazepam. Diazepam and triazolam had significant effects on visual, auditory, attention, emergency immobilization, reaction and hand-eye coordination. New non-benzodiazepine hypnotic drugs such as zolpidem, Zaleplon and zopicron could lead to the decrease of psychomotor ability and neuropsychological ability test scores. Amitriptyline, imipramine and dopamethasone antidepressants can trigger significant impairment of the person's ability to maintain lateral position, vision, response, vigilance and tolerance; Antihistamines such as phenhydramine, hydroxazine, midazolastine and dextralphenamine significantly increased the lateral position standard deviation and speed deviation during driving. The effects of opioids such as codeine on the selective reaction time and somnolence of the users were prominent. Carbamazepine and O'Casey 's equal antiepileptic drugs reduced driveway retention and subjective evaluation, increased driving errors and sleepiness.
【作者單位】: 中國礦業(yè)大學(xué)體育學(xué)院;Dept.of
【基金】:教育部人文社會科學(xué)研究規(guī)劃基金/青年基金/自籌經(jīng)費(fèi)項(xiàng)目(No.14YJA890020) 國家留學(xué)基金委員會青年骨干教師出國研修項(xiàng)目(No.201606425047)
【分類號】:R971
【正文快照】: [37]謝燕燕,鄧昭玲,張嵩,等.西咪替丁治療反復(fù)發(fā)作性急性間歇性卟啉病1例[J].中華內(nèi)科雜志,2016,55(8):640-642.[38]Longhini R,Aparecida de Oliveira P,Sasso-Cerri E,etal.Cimetidine reduces alveolar bone loss in induced peri-odontitis in rat molars[J].J Periodonto,
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