本文關(guān)鍵詞： 超負(fù)荷心肌病 鐵代謝 鐵超負(fù)荷 氧化應(yīng)激 雄性動(dòng)物 雌性小鼠 心臟功能 調(diào)素 野生型小鼠 卵巢切除 　出處：《中華高血壓雜志》2017年03期 　論文類(lèi)型：期刊論文

【摘要】：正人類(lèi)和實(shí)驗(yàn)動(dòng)物中存在心臟功能和鐵代謝的性別相關(guān)差異。男性患者和雄性動(dòng)物模型更易患心肌病和心力衰竭。然而,在鐵超負(fù)荷性心肌病中是否存在類(lèi)似差異并不清楚。方法和結(jié)果:雄性和雌性野生型小鼠和鐵調(diào)素調(diào)節(jié)蛋白(hemojuvelin)缺陷小鼠分別注
[Abstract]:There are sex-related differences in heart function and iron metabolism between humans and laboratory animals. Male patients and male animal models are more susceptible to cardiomyopathy and heart failure. It is not clear whether there is a similar difference in iron overload cardiomyopathy. Methods and results: male and female wild-type mice and iron-regulated protein hemojuvelin deficient mice were injected separately
【分類(lèi)號(hào)】：R54
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本文編號(hào)：1518727