MRI是炎癥性腸病（IBD）診斷和療效評(píng)估的重要檢查手段。隨著納米技術(shù)的發(fā)展,分子對(duì)比劑靶向成像成為可能,但目前有關(guān)分子對(duì)比劑的臨床應(yīng)用多局限于神經(jīng)和循環(huán)系統(tǒng)疾病診斷,有關(guān)IBD診斷的研究較少。腸道的吸收功能以及炎癥時(shí)白細(xì)胞的大量聚集為腸道病變分子對(duì)比劑靶向成像提供了理論基礎(chǔ)。本文就分子對(duì)比劑MRI在IBD中的應(yīng)用研究進(jìn)展作一綜述。 

【文章來(lái)源】：浙江醫(yī)學(xué). 2020,42(08)

【文章頁(yè)數(shù)】：4 頁(yè)

【文章目錄】：
1 分子對(duì)比劑吸收機(jī)制
2 分子對(duì)比劑選擇
    2.1 MNPs
    2.2 釓相關(guān)NPs
    2.3 PFC
3 成像優(yōu)化
4 局限性與未來(lái)展望
5 小結(jié)


【參考文獻(xiàn)】：
期刊論文
[1]Bimodal visualization of colorectal uptake of nanoparticles in dimethylhydrazine-treated mice[J]. Tao Wu,Wei-Liang Zheng,Shi-Zheng Zhang,Ji-Hong Sun,Hong YuanTao Wu,Wei-Liang Zheng,Shi-Zheng Zhang,Department of Radiology,Sir Run Run Shaw Hospital,School of Medicine,Zhejiang University,No.3 Qingchun Road East,Hangzhou 310016,Zhejiang Province,China Tao Wu,Department of Radiology,Jining Medical College,Jining 272067,Shandong Province,China Ji-Hong Sun,Department of Radiology,Second Affiliated Hospital,Zhejiang University School of Medicine,Hangzhou 310009,Zhejiang Province,China Hong Yuan,College of Pharmaceutical Sciences,Zhejiang University,Hangzhou 310009,Zhejiang Province,China.  World Journal of Gastroenterology. 2011(31)



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