本文選題：鼻炎　切入點(diǎn)：變應(yīng)性　出處：《首都醫(yī)科大學(xué)》2012年碩士論文

【摘要】：目的 評(píng)價(jià)變應(yīng)性鼻炎(allergic rhinitis, AR)兒童的生活質(zhì)量以及對(duì)兒童鼻-結(jié)膜炎生活質(zhì)量量表調(diào)查表( Pediatric Rhino-conjunctivitis Quality of Life Questionnaire,PRQLQ)中各項(xiàng)評(píng)價(jià)指標(biāo)間的相關(guān)性進(jìn)行分析。 方法 隨機(jī)抽取2006年7月-2007年9月北京兒童醫(yī)院耳鼻喉科對(duì)北京地區(qū)學(xué)齡前3-5歲兒童進(jìn)行AR流行病學(xué)調(diào)查中確診為AR兒童51例,男孩37例,女孩14例,年齡在8.00歲~11.17歲,平均年齡為(9.85±0.85)歲;同期的健康兒童52例,男孩27例,女孩25例,年齡在8.33歲~11.25歲,平均年齡為(9.94±0.71)歲。兩組的年齡無統(tǒng)計(jì)學(xué)差異(t=0.54,P0.05)。再次電話隨訪,AR兒童再次行皮膚點(diǎn)刺試驗(yàn)(Skin Prick Test,SPT),用PRQLQ來評(píng)價(jià)AR兒童的生活質(zhì)量的五方面及23項(xiàng)目,使用SPSS 13.0進(jìn)行統(tǒng)計(jì)學(xué)分析。 結(jié)果 1、AR兒童PRQLQ五方面評(píng)分的均值都明顯高于對(duì)照組,統(tǒng)計(jì)學(xué)有顯著性差異(P0.01)。 2、AR兒童PRQLQ五方面間及23項(xiàng)目間的比較差異有統(tǒng)計(jì)學(xué)意義(F=36.56,P0.01;F=14.71,P0.01)。鼻部癥狀是患兒生活質(zhì)量受影響較明顯的方面(2.52±1.27)。評(píng)分最高的項(xiàng)目依次為鼻塞、鼻癢、流涕、噴嚏(2.47±1.47; 2.55±1.45;2.53±1.42;2.55±1.47),四者間差異無統(tǒng)計(jì)學(xué)意義(P 0.05)。 3、相關(guān)性分析顯示: 3.1鼻部癥狀和鼻炎相關(guān)行為問題顯著相關(guān)(r=0.82,P0.01)�；痦�(xiàng)目:北京市自然科學(xué)基金資助,項(xiàng)目編號(hào):2009/3125 3.2鼻部癥狀和非鼻-結(jié)膜炎癥狀顯著相關(guān)(r=0.74,P0.01)。鼻部癥狀和注意力難以集中顯著相關(guān)(r=0.59,P0.01)。注意力難以集中和鼻癢、流涕呈正相關(guān)(r=0.58,P0.01;r=0.59,P0.01)。難以入睡和鼻癢癥狀顯著相關(guān)(r=0.57,P0.01)。 3.3鼻部癥狀和情感反應(yīng)顯著相關(guān)(r=0.68,P0.01)。鼻部癥狀和尷尬顯著相關(guān)(r=0.66,P0.01)。尷尬和鼻癢、流鼻涕顯著相關(guān)(r=0.58,P0.01;r=0.66,P0.01)。 3.4鼻部癥狀和眼部癥狀顯著相關(guān)(r=0.56,P0.01)。 3.5鼻炎相關(guān)行為問題和情感反應(yīng)顯著相關(guān)(r=0.74,P0.01)。尷尬和需攜帶面巾紙、需揉鼻或眼顯著相關(guān)(r=0.65,P0.01;r=0.58,P0.01)。 結(jié)論 1、AR兒童的生活質(zhì)量較健康兒童受到更為明顯的影響。 2、鼻部癥狀是兒童患者生活質(zhì)量最受影響的方面。鼻塞、鼻癢、流涕、噴嚏是患兒最常見的癥狀。 3、相關(guān)性分析提示:鼻部癥狀可能是影響鼻炎相關(guān)行為問題、非鼻-結(jié)膜炎癥狀、情感反應(yīng)的主要原因。鼻炎相關(guān)行為問題可能是導(dǎo)致情感反應(yīng)的主要原因。
[Abstract]:PurposeMethodFrom July 2006 to September 2007, 51 children (37 boys and 14 girls) were diagnosed as AR by the otolaryngology department of Beijing Children's Hospital from July 2006 to September 2007. Their age was 8.00 years old or 11.17 years old.The mean age was 9.85 鹵0.85 years, and 52 healthy children, 27 boys and 25 girls, aged from 8.33 years to 11.25 years, with an average age of 9.94 鹵0.71 years.There was no significant difference in age between the two groups.The skin Prick test was used to evaluate the five aspects and 23 items of quality of life of AR children by PRQLQ. SPSS 13.0 was used for statistical analysis.Result1the mean PRQLQ score of children with AR was significantly higher than that of the control group (P 0.01).(2) there were significant differences between the five aspects of PRQLQ in children with AR and the differences among the 23 items. There was a significant difference between them (P = 36.56, P = 0.01F = 14.71, P = 0.01a, P = 0.01a, P = 0.01).Nasal symptoms were significantly affected by the quality of life of the children (2.52 鹵1.27).The highest scores were nasal congestion, itching, runny nose, sneezing 2.47 鹵1.47 and 2.55 鹵1.45 ~ 2.53 鹵1.42 ~ 2.55 鹵1.47 respectively. There was no significant difference among the four groups (P 0.05).3. Correlation analysis shows that:3.1 there was a significant correlation between nasal symptoms and rhinitis related behavioral problems (P 0.01).Project: supported by Beijing Natural Science Foundation, Project No.: 2009 / 31253.2 there was a significant correlation between nasal symptoms and non-rhinoconjunctivitis symptoms (P 0.01).There was a significant correlation between nasal symptoms and attention.There was a positive correlation between nasal itching and distraction, and there was a positive correlation between the volume of rhizoid and the rhizoid concentration of 0.58% (P 0.01) and 0.59% (P 0.01).There was a significant correlation between the difficulty of falling asleep and the symptoms of nasal itching.3.3 there was a significant correlation between nasal symptoms and emotional responses.Nasal symptoms were significantly correlated with embarrassment (P 0.01).Embarrassed and itchy nose, runny nose was significantly correlated with 0.58% P 0.01 ~ 0.66% ~ 0.66% P _ (0.01) ~ 0. 01%.3.4 there was a significant correlation between nasal symptoms and ocular symptoms.3.5 there was a significant correlation between rhinitis related behavioral problems and affective responses (P 0.01).Embarrassment and need to carry face napkin, need to rub nose or eyes significantly related to 0.65% P0.01A 0.58% P0.01C.ConclusionThe quality of life of AR children was significantly affected than that of healthy children.2. Nasal symptoms are the most affected aspect of children's quality of life.Stuffiness, itching, runny nose and sneezing are the most common symptoms in children.3, correlation analysis suggests that nasal symptoms may be the main cause of affecting rhinitis related behavioral problems, non-nasopharyngeal conjunctivitis symptoms and emotional reactions.Rhinitis-related behavioral problems may be the main cause of emotional response.
【學(xué)位授予單位】：首都醫(yī)科大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2012
【分類號(hào)】：R765.21

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