【摘要】：目的利用不同人體測(cè)量指標(biāo),調(diào)查分析成都地區(qū)50歲以上男性居民中肥胖與骨質(zhì)疏松的相關(guān)性。方法采集在四川大學(xué)華西醫(yī)院進(jìn)行健康體檢的50歲以上男性受檢者的臨床資料,并測(cè)量和計(jì)算不同人體測(cè)量參數(shù)。使用MetriScan手掌骨密度測(cè)量?jī)x進(jìn)行骨密度測(cè)定,并根據(jù)T值將受試者分為3組(正常骨密度組、骨量減少組和骨質(zhì)疏松組),比較各組間肥胖的檢出率。將體質(zhì)量指數(shù)(BMI)、體圓柱指數(shù)(BRI)、腰圍、腰高比(WHtR)、腰臀比(WHR)、身體形態(tài)指數(shù)(ABSI)和身高等人體測(cè)量參數(shù)分別按四分位數(shù)等分為Q1、Q2、Q3、Q4四組,均以Q1組為參照組,采用單因素及年齡矯正后的多元logistic回歸分析上述人體測(cè)量參數(shù)與骨質(zhì)疏松檢出風(fēng)險(xiǎn)的關(guān)系。同時(shí)計(jì)算各指標(biāo)受試者操作特征(ROC)曲線的曲線下面積(AUC)。結(jié)果共納入9 135例成都地區(qū)50歲以上男性居民,其中骨質(zhì)疏松癥的檢出率為5.75%(525例)。骨質(zhì)疏松組各種人體測(cè)量參數(shù)(BMI、WHR、WHtR、體質(zhì)量、腰圍、臀圍、ABSI、BRI等)與骨量減少組和正常骨密度組比較差異具有統(tǒng)計(jì)學(xué)意義(P0.01)。與最低四分位數(shù)(Q1)組相比,BMI、BRI、WHtR、WHR、ABSI、腰圍和身高的最高四分位數(shù)(Q4)組受檢者合并骨質(zhì)疏松的經(jīng)年齡矯正的比值比分別為0.443〔95%可信區(qū)間(CI):0.342~0.574〕、0.580(95%CI:0.454~0.740)、0.587(95%CI:0.460~0.751)、0.664(95%CI:0.516~0.854)、1.369(95%CI:1.069~1.751)、0.634(95%CI:0.497~0.809)、1.357(95%CI:1.047~1.758)。ROC曲線分析顯示,BMI對(duì)骨質(zhì)疏松的AUC為0.606(95%CI:0.580~0.632)。結(jié)論肥胖與男性骨質(zhì)疏松呈一定的負(fù)相關(guān),利用BMI測(cè)量的肥胖對(duì)男性骨質(zhì)疏松有潛在的預(yù)測(cè)價(jià)值,需要進(jìn)一步的縱向研究明確其臨床意義。
[Abstract]:Objective to investigate the correlation between obesity and osteoporosis in male residents over 50 years old in Chengdu. Methods the clinical data of male subjects over 50 years old who underwent physical examination in Huaxi Hospital of Sichuan University were collected, and different anthropometric parameters were measured and calculated. MetriScan palm bone mineral density instrument was used to measure bone mineral density. According to T value, the subjects were divided into three groups (normal bone mineral density group, bone mass reduction group and osteoporosis group). The detection rate of obesity among groups was compared. The body mass index (BMI), body cylinder index (BRI), waist circumference, waist height ratio (WHtR), waist hip ratio (WHR), body shape index (ABSI) and height were divided into Q1, Q2, Q3, Q4 groups according to the quartile, respectively. The relationship between the above anthropometric parameters and the risk of osteoporosis was analyzed by single factor and age corrected multiple logistic regression. At the same time, the area (AUC). Under the curve of the operating characteristic (ROC) curve of the subjects was calculated. Results A total of 9135 male residents over 50 years old in Chengdu were included, of which the detection rate of osteoporosis was 5.75% (525 cases). There were significant differences in various anthropometric parameters (BMI,WHR,WHtR, body mass, waist circumference, hip circumference, ABSI,BRI, etc.) between osteoporosis group and bone mass reduction group and normal bone mineral density group (P 0.01). Compared with the lowest quartile group (Q1), the age-corrected ratio of BMI,BRI,WHtR,WHR,ABSI, waist circumference to height quartile (Q4) group was 0.443 (95% confidence interval (CI): 0.342 鈮，

本文編號(hào)：2522293