發(fā)布時間：2019-07-09 20:31

【摘要】：目的了解2型糖尿病(T2DM)患者認(rèn)知功能損害的情況及其危險(xiǎn)因素。方法應(yīng)用簡易智能精神狀態(tài)量表(MMSE)評估年齡、性別、文化程度和居住地相匹配的250例T2DM患者和250例對照者的認(rèn)知功能,并將糖尿病組按年齡、病程、血糖控制水平、并發(fā)癥與認(rèn)知功能障礙進(jìn)行單因素分析。結(jié)果糖尿病組MMSE總分,尤其是記憶、注意與計(jì)算力、語言能力、視空間、時間和地點(diǎn)定向得分顯著低于對照組(P0.05,P0.01)。糖尿病組認(rèn)知功能障礙與年齡、病程、血糖控制水平、合并高血壓、高血脂、冠心病等因素均有統(tǒng)計(jì)學(xué)意義(P0.05;P0.01)。未發(fā)現(xiàn)糖尿病治療方法與認(rèn)知功能有明顯的關(guān)系。結(jié)論認(rèn)知功能減退與T2DM有關(guān)。嚴(yán)格控制血糖、血壓,調(diào)整血脂等手段是改善認(rèn)知功能的重要措施。
[Abstract]:Objective to investigate the cognitive impairment and its risk factors in patients with type 2 diabetes mellitus (T2DM). Methods the cognitive function of 250 T2DM patients and 250 controls matched with age, sex, educational level and place of residence were evaluated by simple Mental State scale (MMSE). Univariate analysis was made on the cognitive function of diabetic group according to age, course of disease, blood glucose control level, complications and cognitive impairment. Results the total score of MMSE, especially memory, attention and calculation, language ability, visual space, time and place orientation, in diabetic group were significantly lower than those in control group (P0.05, P0.01). In diabetic group, cognitive impairment and age, course of disease, blood glucose control level, hypertension, hyperlipidemia, coronary heart disease and other factors were statistically significant (P0.05 鈮，

本文編號：2512425