2型糖尿病及糖尿病足患者血清唾液酸的變化及意義
[Abstract]:Objective to study the changes of serum sialic acid (SA) in patients with type 2 diabetes mellitus (T2DM) and diabetic foot (DF). Methods fasting blood glucose (FPG), glycosylated hemoglobin (Hb A1c) was measured in 93 patients with T2DM and 52 healthy people with age, sex and body mass index (BMI). T2 DM patients included 53 patients with simple diabetes mellitus and 40 patients with DF. At the same time, the working curve (ROC) of 40 patients with DF and 52 healthy subjects (normal control group, NC group) was drawn and the value of SA was evaluated by correlation analysis. Results the critical value of serum SA determined by ROC was 639.95 mg/L, and the specificity of SA in 90.38%.DF group was significantly higher than that in T2DM group and NC group (P 0.05). There was a positive correlation between SA and FPG and Hb A1c. Conclusion SA is significantly increased in T2DM and DF. Detection of serum SA is of great significance in judging DF.
【作者單位】: 華中科技大學同濟醫(yī)學院附屬梨園醫(yī)院檢驗科;華中科技大學同濟醫(yī)學院附屬梨園醫(yī)院骨科;
【分類號】:R446.1;R587.2
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