【摘要】：目的：評(píng)價(jià)STOP-Bang問(wèn)卷在代謝綜合征(MS)患者中預(yù)測(cè)阻塞性睡眠呼吸暫停(OSA)的能力。方法：分析2013年12月至2014年5月在新疆醫(yī)科大學(xué)第一附屬醫(yī)院睡眠監(jiān)測(cè)室行睡眠監(jiān)測(cè)(PSG)的317例MS患者的STOP-Bang問(wèn)卷及PSG監(jiān)測(cè)結(jié)果。根據(jù)PSG結(jié)果將患者分為非OSA組及OSA組(輕、中、重度OSA組),比較各組間性別、STOP-Bang評(píng)分及低通氣指數(shù)(AHI)等結(jié)果的差異。分析問(wèn)卷與PSG監(jiān)測(cè)指標(biāo)間相關(guān)性。應(yīng)用四格表分析STOP-Bang問(wèn)卷在不同AHI分界點(diǎn)下的靈敏度、特異度、陽(yáng)性預(yù)測(cè)值、陰性預(yù)測(cè)值。繪制受試者工作特征(ROC)曲線。結(jié)果：非OSA組與OSA組性別構(gòu)成比、年齡、頸圍、腹圍、收縮壓、舒張壓、BMI、 HDL-c差異有統(tǒng)計(jì)學(xué)意義(P均0.01)。非OSA組與其他各組的STOP-Bang評(píng)分結(jié)果差異均有統(tǒng)計(jì)學(xué)意義(P0.001)。四組STOP-Bang評(píng)分隨嚴(yán)重程度增加呈逐漸增高趨勢(shì)(2.30±1.01,3.48+1.30,3.82±1.26,4.57±1.43)。以3分為截點(diǎn)篩查入選的MS患者是否患OSA,靈敏度為86.36%,特異度為50.94%。以4分為截點(diǎn)預(yù)測(cè)是否患OSA、中重度OSA、重度OSA, Youden指數(shù)均最高。當(dāng)AHI≥5, AHI15, AHI30時(shí),ROC曲線下面積分別為0.824,0.851,0.892,P均0.001。結(jié)論：STOP-Bang問(wèn)卷在MS人群中應(yīng)用具有良好的可行性和準(zhǔn)確性,值得推廣使用。
[Abstract]:Objective: to evaluate the ability of STOP-Bang questionnaire to predict obstructive sleep apnea (OSA) in patients with metabolic syndrome (MS). Methods: from December 2013 to May 2014, 317 cases of MS patients who received sleep monitoring in sleep monitoring room of the first affiliated Hospital of Xinjiang Medical University were analyzed STOP-Bang questionnaire and PSG monitoring results. According to the results of PSG, the patients were divided into non-OSA group and OSA group (mild, moderate and severe OSA group). The differences of sex, STOP-Bang score and (AHI) were compared. The correlation between questionnaire and PSG monitoring index was analyzed. The sensitivity, specificity, positive predictive value and negative predictive value of STOP-Bang questionnaire at different AHI boundary points were analyzed by four-grid table. The (ROC) curves of the operating characteristics of the subjects were drawn. Results: there were significant differences in sex composition ratio, age, neck circumference, abdominal circumference, systolic blood pressure, diastolic blood pressure and BMI, HDL-c between non OSA group and OSA group (all P 0.01). There was significant difference in STOP-Bang score between non-OSA group and other groups (P 0. 001). The STOP-Bang scores of the four groups increased gradually with the increase of severity (2.30 鹵1.01 鹵3.48 1.30 鹵3.82 鹵1.26 鹵4.57 鹵1.43). The sensitivity and specificity of OSA, were 86.36 and 50.944 in MS patients who were selected by 3-cut screening. The highest OSA, Youden index of moderate and severe OSA, was predicted by 4-cut points. When AHI 鈮，

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