肥胖對男性生殖細胞功能的影響及其機制研究進展
發(fā)布時間:2018-10-19 19:33
【摘要】:肥胖可導致男性生殖功能下降,表現(xiàn)為精子數(shù)量和精液質(zhì)量下降、附睪中精子運動功能下降。其發(fā)生機制包括肥胖影響性激素分泌、促進生精細胞凋亡、促進氧化應激和導致生殖細胞表觀遺傳學改變。
[Abstract]:Obesity can lead to the decrease of male reproductive function, which is manifested by the decrease of sperm quantity and semen quality, and the decrease of sperm motility in epididymis. The mechanisms include obesity affecting the secretion of sex hormones, promoting the apoptosis of spermatogenic cells, promoting oxidative stress and leading to epigenetic changes of germ cells.
【作者單位】: 延邊大學醫(yī)學院;吉林醫(yī)藥學院公共衛(wèi)生學院;
【基金】:國家自然科學基金項目(81472964) 吉林省自然科基金項目(201501012065C)
【分類號】:R589.2
本文編號:2282149
[Abstract]:Obesity can lead to the decrease of male reproductive function, which is manifested by the decrease of sperm quantity and semen quality, and the decrease of sperm motility in epididymis. The mechanisms include obesity affecting the secretion of sex hormones, promoting the apoptosis of spermatogenic cells, promoting oxidative stress and leading to epigenetic changes of germ cells.
【作者單位】: 延邊大學醫(yī)學院;吉林醫(yī)藥學院公共衛(wèi)生學院;
【基金】:國家自然科學基金項目(81472964) 吉林省自然科基金項目(201501012065C)
【分類號】:R589.2
【相似文獻】
相關期刊論文 前1條
1 石金鳳;謝遠杰;李美香;龍治峰;鄭翔;趙國軍;杜雅蘭;賀麗萍;;L-NAME對大鼠生精細胞p53表達的影響[J];中國熱帶醫(yī)學;2012年04期
,本文編號:2282149
本文鏈接:http://sikaile.net/yixuelunwen/nfm/2282149.html
最近更新
教材專著