【摘要】：目的:對(duì)新診斷II型糖尿病患者進(jìn)行胰島素聯(lián)合黃芪消渴方治療效果對(duì)比研究。方法:120例患者采用隨機(jī)數(shù)字法分為兩組,對(duì)照組60例患者采用單純胰島素治療,觀察者60例患者采用胰島素聯(lián)合黃芪消渴方治療,比較兩組患者的血糖水平與控制血糖的臨床療效情況。結(jié)果:觀察組(胰島素聯(lián)合黃芪消渴方)患者的空腹血糖、餐后2h血糖值以及糖化血紅蛋白值均低于對(duì)照組(單純使用胰島素)患者水平,兩組比較差異具有統(tǒng)計(jì)學(xué)意義(P0.05)。同時(shí)將治療后與治療前比較,兩組患者體重指數(shù)變化無顯著性差異,而空腹血糖、餐后2 h血糖以及糖化血紅蛋白值治療后均降低,差異具有統(tǒng)計(jì)學(xué)意義(P0.05)。觀察組患者治療1個(gè)周后的空腹血糖達(dá)標(biāo)率與餐后2h血糖達(dá)標(biāo)率以及糖化血紅蛋白達(dá)標(biāo)率均高于對(duì)照組患者,兩組比較差異具有統(tǒng)計(jì)學(xué)意義(P0.05)。觀察組未出現(xiàn)低血糖事件,對(duì)照組有2例出現(xiàn)低血糖情況,經(jīng)簡單處理恢復(fù),兩組均未出現(xiàn)嚴(yán)重的不良事件。觀察組的達(dá)標(biāo)時(shí)間以及胰島素的用量均低于對(duì)照組,兩組比較差異具有統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論:胰島素聯(lián)合黃芪消渴方對(duì)于新診斷2型糖尿病患者治療依從性高,并且臨床療效好、安全性高。
[Abstract]:Objective: to compare the therapeutic effect of insulin combined with Huangqi Xiaoke recipe in newly diagnosed type 2 diabetes mellitus. Methods 120 patients were randomly divided into two groups: the control group (n = 60) was treated with insulin alone and the observer (n = 60) with insulin combined with Huangqi Xiaoke recipe. To compare the blood glucose level and the clinical effect of blood sugar control between the two groups. Results: the fasting blood glucose, 2 h postprandial blood glucose and glycosylated hemoglobin in the observation group (insulin combined with Huangqi Xiaoke recipe) were lower than those in the control group (P 0.05). At the same time, compared with before treatment, there was no significant difference in body mass index between the two groups, but fasting blood glucose, postprandial blood glucose and glycosylated hemoglobin decreased after treatment, the difference was statistically significant (P0.05). The rates of fasting blood glucose and 2 h postprandial blood glucose and glycosylated hemoglobin in the observation group were higher than those in the control group after 1 week of treatment. The difference between the two groups was statistically significant (P0.05). There were no hypoglycemic events in the observation group and two cases in the control group. The time of meeting the standard and the dosage of insulin in the observation group were lower than those in the control group, and the difference between the two groups was statistically significant (P0.05). Conclusion: insulin combined with Huangqi Xiaoke recipe has high compliance, good clinical efficacy and high safety for newly diagnosed type 2 diabetic patients.
【作者單位】： 棗莊礦業(yè)集團(tuán)中心醫(yī)院;上海交通大學(xué)附屬醫(yī)院;
【基金】：上海市青浦區(qū)科學(xué)技術(shù)發(fā)展基金項(xiàng)目(12-E-21)
【分類號(hào)】：R587.1

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