狼瘡性膀胱炎的臨床特征及危險因素分析
發(fā)布時間：2018-07-15 20:37
【摘要】：目的分析狼瘡性膀胱炎患者的臨床特征及危險因素。方法選取27例確診的狼瘡性膀胱炎的住院患者作為病例組,并選取性別、年齡及病程相匹配的無狼瘡性膀胱炎的系統(tǒng)性紅斑狼瘡(SLE)住院患者共135例作為對照組,回顧性分析兩組間臨床表現、實驗室檢查與影像學的差異;通過Logistic回歸分析初步探討狼瘡性膀胱炎的危險因素。結果狼瘡性膀胱炎的發(fā)生率1.3%,主要表現為下尿路癥狀、雙側輸尿管擴張及腎積水等;與對照組相比,狼瘡性膀胱炎患者的胃腸道癥狀的發(fā)生率高于無狼瘡性膀胱炎的患者,但狼瘡性腎炎和蛋白尿的發(fā)生率低于后者,差異有統(tǒng)計學意義(P0.05);SLE合并狼瘡性膀胱炎組患者補體低于對照組,抗SSA抗體的陽性率高于對照組(P0.05);狼瘡性膀胱炎組SLEDAI評分低于對照組(P0.05);Logistic回歸分析發(fā)現胃腸道癥狀、低補體為狼瘡性膀胱炎的危險因素。結論胃腸道癥狀及低補體為狼瘡性膀胱炎的危險因素,抗SSA抗體與狼瘡性膀胱炎密切相關。
[Abstract]:Objective to analyze the clinical characteristics and risk factors of lupus cystitis patients. Methods 27 hospitalized patients with lupus cystitis were selected as a case group, and 135 patients with systemic lupus erythematosus (SLE) without lupus cystitis (SLE) were selected as the control group. The retrospective analysis of the two groups was used as a control group. The difference in bed performance, laboratory examination and imaging; the risk factors for lupus cystitis were preliminarily studied by Logistic regression analysis. Results the incidence of lupus cystitis was 1.3%, mainly characterized by lower urinary tract symptoms, bilateral ureteral dilatation and hydronephrosis, compared with the control group, and the occurrence of gastrointestinal symptoms in patients with lupus cystitis. The rate was higher than the patients without lupus cystitis, but the incidence of lupus nephritis and proteinuria was lower than the latter, the difference was statistically significant (P0.05); SLE combined with lupus cystitis group was lower than the control group, the positive rate of anti SSA antibody was higher than that of the control group (P0.05); the SLEDAI score of the lupus cystitis group was lower than the control group (P0.05); Logistic returns to the group of lupus cystitis group (P0.05); Gastrointestinal symptoms and low complement are the risk factors for lupus cystitis. Conclusion gastrointestinal symptoms and low complement are risk factors for lupus cystitis. Anti SSA antibody is closely related to lupus cystitis.
【作者單位】： 中南大學湘雅醫(yī)院風濕免疫科;
【基金】：2015年度“湘雅醫(yī)院-北大未名臨床與康復研究基金”(No:xywm2015118)
【分類號】：R593.24;R694.3
本文編號：2125310
[Abstract]:Objective to analyze the clinical characteristics and risk factors of lupus cystitis patients. Methods 27 hospitalized patients with lupus cystitis were selected as a case group, and 135 patients with systemic lupus erythematosus (SLE) without lupus cystitis (SLE) were selected as the control group. The retrospective analysis of the two groups was used as a control group. The difference in bed performance, laboratory examination and imaging; the risk factors for lupus cystitis were preliminarily studied by Logistic regression analysis. Results the incidence of lupus cystitis was 1.3%, mainly characterized by lower urinary tract symptoms, bilateral ureteral dilatation and hydronephrosis, compared with the control group, and the occurrence of gastrointestinal symptoms in patients with lupus cystitis. The rate was higher than the patients without lupus cystitis, but the incidence of lupus nephritis and proteinuria was lower than the latter, the difference was statistically significant (P0.05); SLE combined with lupus cystitis group was lower than the control group, the positive rate of anti SSA antibody was higher than that of the control group (P0.05); the SLEDAI score of the lupus cystitis group was lower than the control group (P0.05); Logistic returns to the group of lupus cystitis group (P0.05); Gastrointestinal symptoms and low complement are the risk factors for lupus cystitis. Conclusion gastrointestinal symptoms and low complement are risk factors for lupus cystitis. Anti SSA antibody is closely related to lupus cystitis.
【作者單位】： 中南大學湘雅醫(yī)院風濕免疫科;
【基金】：2015年度“湘雅醫(yī)院-北大未名臨床與康復研究基金”(No:xywm2015118)
【分類號】：R593.24;R694.3
【相似文獻】
相關期刊論文 前1條
1 ;胃腸道癥狀提示狼瘡性膀胱炎[J];中國社區(qū)醫(yī)師;2011年10期
，本文編號：2125310
本文鏈接：http://sikaile.net/yixuelunwen/nfm/2125310.html
最近更新
教材專著
