【摘要】：目的分析狼瘡性膀胱炎患者的臨床特征及危險(xiǎn)因素。方法選取27例確診的狼瘡性膀胱炎的住院患者作為病例組,并選取性別、年齡及病程相匹配的無(wú)狼瘡性膀胱炎的系統(tǒng)性紅斑狼瘡(SLE)住院患者共135例作為對(duì)照組,回顧性分析兩組間臨床表現(xiàn)、實(shí)驗(yàn)室檢查與影像學(xué)的差異;通過(guò)Logistic回歸分析初步探討狼瘡性膀胱炎的危險(xiǎn)因素。結(jié)果狼瘡性膀胱炎的發(fā)生率1.3%,主要表現(xiàn)為下尿路癥狀、雙側(cè)輸尿管擴(kuò)張及腎積水等;與對(duì)照組相比,狼瘡性膀胱炎患者的胃腸道癥狀的發(fā)生率高于無(wú)狼瘡性膀胱炎的患者,但狼瘡性腎炎和蛋白尿的發(fā)生率低于后者,差異有統(tǒng)計(jì)學(xué)意義(P0.05);SLE合并狼瘡性膀胱炎組患者補(bǔ)體低于對(duì)照組,抗SSA抗體的陽(yáng)性率高于對(duì)照組(P0.05);狼瘡性膀胱炎組SLEDAI評(píng)分低于對(duì)照組(P0.05);Logistic回歸分析發(fā)現(xiàn)胃腸道癥狀、低補(bǔ)體為狼瘡性膀胱炎的危險(xiǎn)因素。結(jié)論胃腸道癥狀及低補(bǔ)體為狼瘡性膀胱炎的危險(xiǎn)因素,抗SSA抗體與狼瘡性膀胱炎密切相關(guān)。
[Abstract]:Objective to analyze the clinical characteristics and risk factors of lupus cystitis patients. Methods 27 hospitalized patients with lupus cystitis were selected as a case group, and 135 patients with systemic lupus erythematosus (SLE) without lupus cystitis (SLE) were selected as the control group. The retrospective analysis of the two groups was used as a control group. The difference in bed performance, laboratory examination and imaging; the risk factors for lupus cystitis were preliminarily studied by Logistic regression analysis. Results the incidence of lupus cystitis was 1.3%, mainly characterized by lower urinary tract symptoms, bilateral ureteral dilatation and hydronephrosis, compared with the control group, and the occurrence of gastrointestinal symptoms in patients with lupus cystitis. The rate was higher than the patients without lupus cystitis, but the incidence of lupus nephritis and proteinuria was lower than the latter, the difference was statistically significant (P0.05); SLE combined with lupus cystitis group was lower than the control group, the positive rate of anti SSA antibody was higher than that of the control group (P0.05); the SLEDAI score of the lupus cystitis group was lower than the control group (P0.05); Logistic returns to the group of lupus cystitis group (P0.05); Gastrointestinal symptoms and low complement are the risk factors for lupus cystitis. Conclusion gastrointestinal symptoms and low complement are risk factors for lupus cystitis. Anti SSA antibody is closely related to lupus cystitis.
【作者單位】： 中南大學(xué)湘雅醫(yī)院風(fēng)濕免疫科;
【基金】：2015年度“湘雅醫(yī)院-北大未名臨床與康復(fù)研究基金”(No:xywm2015118)
【分類號(hào)】：R593.24;R694.3

【相似文獻(xiàn)】

相關(guān)期刊論文 前1條

1 ;胃腸道癥狀提示狼瘡性膀胱炎[J];中國(guó)社區(qū)醫(yī)師;2011年10期

，

本文編號(hào)：2125310