本文選題：抗阻運動 + 糖尿病前期��； 參考：《中國現(xiàn)代醫(yī)學雜志》2017年28期

【摘要】：目的研究不同運動方式對社區(qū)糖尿病前期(IGR)人群血壓的控制效果。方法于2015年6~8月在桂林的3個社區(qū)衛(wèi)生服務中心長期管理的社區(qū)居民中篩選出符合標準的IGR合并輕度高血壓人群83人,隨機分為3組,經(jīng)過1年的干預和隨訪,最終收集到67人的完整數(shù)據(jù):抗阻運動組22人、有氧運動組23人、對照組22人。干預期間,對照組保持原有的生活方式,抗阻和有氧運動組分別進行相應的運動干預,約50 min/次,以集體形式隔天訓練。對干預后3、6、12個月抽血查空腹血糖、空腹胰島素和糖化血紅蛋白(HbA1c),測血壓,計算胰島素抵抗指數(shù)(HOMA-IR)。結果 (1)不同時間點之間的HbA1c、HOMA-IR、收縮壓(SBP)、舒張壓(DBP)比較,差異有統(tǒng)計學意義(F=22.415、9.289、32.689和6.713,均P=0.000);3組間的HbA1c、HOMA-IR、SBP、DBP比較,差異有統(tǒng)計學意義(F=16.525、4.241、26.436和4.653,P=0.000、0.044、0.000和0.013),干預后抗阻運動組和有氧運動組的HbA1c、HOMA-IR、SBP、DBP低于對照組;3組的HbA1c、HOMA-IR、SBP、DBP變化趨勢差異有統(tǒng)計學意義(F=19.134、4.782、22.520和6.792,均P=0.000),干預期間,對照組各指標總體呈上升趨勢,兩運動組各指標總體呈下降趨勢,雖然兩運動組不同時段各指標比較差異無統(tǒng)計學意義(P0.05),但抗阻運動組的HbA1c、HOMAIR的下降幅度大于有氧運動組,且SBP、DBP下降幅度小于有氧運動組。(2)干預3個月時,有氧和抗阻運動組的HbA1c、HOMA-IR、DBP均低于干預前,有氧運動組SBP低于干預前;干預6個月時,有氧和抗阻運動組的HbA1c、SBP、DBP均低于干預前,抗阻運動組HOMA-IR低于干預前;干預12個月時,有氧和抗阻運動組的HbA1c、HOMA-IR、SBP、DBP均低于干預前,對照組HbA1c、SBP高于干預前,均差異有統(tǒng)計學意義(P0.05)。結論抗阻和有氧運動均能安全有效地改善社區(qū)IGR合并輕度高血壓人群的HbA1c、血壓、HOMA-IR,值得推廣。
[Abstract]:Objective to study the control effect of different exercise ways on blood pressure in community pre-diabetic (IGR) population. Methods from June to August 2015, 83 residents with IGR combined with mild hypertension were selected from three community health service centers in Guilin. They were randomly divided into 3 groups. After one year's intervention and follow-up, 83 patients were selected. Finally, the complete data of 67 subjects were collected: resistance exercise group (22 cases), aerobic exercise group (23 cases) and control group (22 cases). During the intervention, the control group maintained the original lifestyle, the resistance group and the aerobic exercise group respectively carried out corresponding exercise intervention, about 50 min/, in the form of group training every other day. Fasting blood glucose, fasting insulin and glycosylated hemoglobin (HbA1c) were measured at 6 and 12 months after intervention, blood pressure was measured and insulin resistance index (HOMA-IR) was calculated. Results (1) there were significant differences in HOMA-IRR, SBP and DBP between different time points (F: 22.415, 9.28932.689 and 6.713, all P = 0.000). The difference was statistically significant (F _ (16.525) 4.241 ~ 26.436 and 4.653P ~ (0.000) 0.04 ~ 0.000 and 0.013). After intervention, the changes of HBA1cHOMA-IRMA-SBP+ DBP in the anti-resistance exercise group and aerobic exercise group were significantly lower than those in the control group (P < 0.05). During the intervention period, the indexes of the control group showed an overall upward trend. Although there was no significant difference between the two groups (P0.05), the decrease of HbA1cU HOMAIR in the resistance exercise group was higher than that in the aerobic exercise group, and there was no significant difference between the two exercise groups in different periods (P0.05), but the decrease of HbA1cHoma IR in the resistance exercise group was higher than that in the aerobic exercise group. The decrease of SBP in aerobic exercise group was lower than that in aerobic exercise group. (2) after 3 months of intervention, HbA1cHOMA-IRN DBP in aerobic and resistant exercise group was lower than that before intervention, SBP in aerobic exercise group was lower than that before intervention, and HbA1cSBPDBP in aerobic and resistant exercise group was lower than that before intervention for 6 months. HOMA-IR in the resistance exercise group was lower than that before intervention, and at 12 months after intervention, the DBP of HBA1cHoma / IRMA-SBP in the aerobic and resistant exercise groups was lower than that before the intervention, and that in the control group was higher than that before intervention (P0.05). Conclusion both resistance and aerobic exercise can improve HbA1c and HOMA-IRB in community IGR patients with mild hypertension safely and effectively, which is worth popularizing.
【作者單位】： 廣西醫(yī)科大學第一附屬醫(yī)院;廣西醫(yī)科大學護理學院;廣西中醫(yī)藥大學第一附屬醫(yī)院;
【基金】：廣西醫(yī)療衛(wèi)生技術研究與開發(fā)課題項目(No:S201413_03) 廣西研究生教育創(chuàng)新計劃項目(No:YCSZ2015111)
【分類號】：R544.1;R587.1

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