本文選題：甲狀腺細(xì)針穿刺細(xì)胞學(xué) + 超聲引導(dǎo)　； 參考：《臨床與實(shí)驗(yàn)病理學(xué)雜志》2017年08期

【摘要】：目的探討甲狀腺細(xì)針穿刺細(xì)胞學(xué)(fine needle aspiration cytology,FNAC)診斷甲狀腺良、惡性病變漏診率與誤診率。方法收集980例甲狀腺患者在超聲引導(dǎo)下行FNAC檢查,并分析15例甲狀腺FNAC檢查漏診與誤診的原因,以及195例穿刺后行手術(shù)患者的FNAC診斷結(jié)果與術(shù)后病理診斷的一致性。結(jié)果FNAC結(jié)果提示惡性檢出率為11.4%(112/980),穿刺后行手術(shù)的患者195例,術(shù)后病理診斷良性128例,FNAC診斷符合率為91.40%(117/128)。術(shù)后病理診斷,乳頭狀癌60例,FNAC診斷符合率為92.22%(56/60);FNAC檢查誤診11例,漏診4例。結(jié)論超聲引導(dǎo)下甲狀腺FNAC檢查對(duì)甲狀腺術(shù)前良、惡性病變的診斷,尤其對(duì)乳頭狀癌的診斷有一定的漏診率和誤診率,存在一定的局限性。隨著細(xì)胞學(xué)研究的不斷深入,聯(lián)合基因?qū)W及免疫組化協(xié)助診斷,更好地提高甲狀腺FNAC的診斷水平。
[Abstract]:Objective to investigate the rate of missed diagnosis and misdiagnosis of benign and malignant thyroid lesions by (fine needle aspiration cytology. Methods 980 patients with thyroid gland were examined with FNAC under the guidance of ultrasound. The causes of missed diagnosis and misdiagnosis in 15 patients with thyroid FNAC were analyzed. The results of FNAC diagnosis in 195 patients undergoing operation after puncture were consistent with the postoperative pathological diagnosis. Results the positive rate of FNAC was 11.4% (112 / 980), 195 patients underwent operation after puncture and 128 cases of benign FNAC were diagnosed by pathology after operation. The diagnostic coincidence rate of FNAC was 91.40% (117 / 128). The diagnostic coincidence rate of FNAC in 60 cases of papillary carcinoma was 92.22% (56 / 60) misdiagnosed in 11 cases and missed in 4 cases. Conclusion Ultrasound-guided FNAC has some limitations in the diagnosis of benign and malignant thyroid lesions, especially in the diagnosis of papillary carcinoma. With the development of cytological research, the diagnosis of thyroid FNAC can be improved by combining gene and immunohistochemistry.
【作者單位】： 甘肅省腫瘤醫(yī)院病理診斷中心;
【基金】：甘肅省衛(wèi)生行業(yè)計(jì)劃管理項(xiàng)目(GWGL2014-39)
【分類號(hào)】：R581

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本文編號(hào)：2073147