本文選題：血脂異常 + 哈薩克族��； 參考：《石河子大學(xué)》2015年碩士論文

【摘要】：目的:通過對(duì)新疆農(nóng)村地區(qū)哈薩克族、維吾爾族血脂異�；颊唛_展健康教育聯(lián)合藥物治療的綜合干預(yù)研究,評(píng)價(jià)干預(yù)人群的調(diào)脂效果,為新疆農(nóng)村少數(shù)民族治療血脂異常提供科學(xué)依據(jù)。方法:本研究采用分層整群隨機(jī)抽樣方法選擇新疆伊犁新源縣那拉提鎮(zhèn)和喀什伽師縣江巴孜鄉(xiāng)共18個(gè)自然村,隨機(jī)分為干預(yù)村和對(duì)照村。對(duì)上述村中18歲及以上的哈薩克族和維吾爾族常住居民進(jìn)行基線調(diào)查,篩選調(diào)查人群中診斷為血脂異常的患者作為研究對(duì)象。通過入戶訪問的方式收集問卷信息、體檢及血標(biāo)本的采集,干預(yù)組采取減鹽、低脂飲食、多吃蔬菜等健康教育聯(lián)合調(diào)脂藥物辛伐他汀治療,對(duì)照組不采取任何措施,定期入戶隨訪2年。結(jié)局調(diào)查方法及內(nèi)容同基線。采用OLYMPUS 2007全自動(dòng)生化儀檢測(cè)血清總膽固醇(TC)、甘油三酯(TG)、低密度脂蛋白膽固醇(LDL-C)、高密度脂蛋白膽固醇(HDL-C)等指標(biāo)。應(yīng)用SPSS17.0軟件進(jìn)行統(tǒng)計(jì)分析,計(jì)量資料采用(x±s)描述,兩組間均數(shù)的比較用t檢驗(yàn),重復(fù)測(cè)量數(shù)據(jù)采用重復(fù)測(cè)量的方差分析,率或構(gòu)成比的比較采用Pearsonχ2檢驗(yàn)。結(jié)果:1.確定研究對(duì)象784人,干預(yù)組518人、對(duì)照組266人,隨訪3年后共失訪94人,隨訪率88.0%。其中干預(yù)組460人,隨訪率為88.8%;對(duì)照組230人,隨訪率86.5%。2.綜合干預(yù)后,干預(yù)組TG、LDL-C的降低的幅度分別是2.80%、12.12%,HDL-C的上升幅度是23.00%,與對(duì)照組比較,差異均有統(tǒng)計(jì)學(xué)意義(P0.05)。3.干預(yù)組TC、LDL-C水平較基線降低至(4.06±0.94)mmol/L、(2.03±0.61)mmol/L(P0.05),HDL-C水平升高(1.23±0.46)mmol/L(P0.05)。干預(yù)組血脂控制率為38.70%,高于對(duì)照組的3.48%(χ2=62.407,P0.01)。4.通過綜合干預(yù)后,干預(yù)組與對(duì)照組血脂異常知識(shí)平均知曉率分別為26.2%、5.5%,信念平均形成率分別為35.1%、7.5%,行為平均形成率分別為12.9%、3.7%,差異均有統(tǒng)計(jì)學(xué)意義(P0.05)。干預(yù)組血脂異�；颊叩闹R(shí)知曉率、信念形成率、行為形成率均較干預(yù)前明顯提高,差異均有統(tǒng)計(jì)學(xué)意義(P0.05)。5.綜合干預(yù)后,干預(yù)組與對(duì)照組血脂異常知識(shí)得分分別為(3.32±2.19)分、(1.39±1.18)分,態(tài)度得分分別為(2.07±1.27)分、(0.82±0.92)分,行為得分分別為(1.11±1.10)分、(0.70±0.96)分,平均總分分別為(6.50±3.30)分、(2.91±2.31)分,且兩組均有差異(P0.01)。結(jié)論:通過為期3年的健康教育聯(lián)合藥物治療綜合干預(yù),干預(yù)組血脂異常患者血脂水平均有所改善,改善幅度優(yōu)于對(duì)照組,4項(xiàng)血脂水平控制率明顯提高,知識(shí)知曉率、信念形成率、行為形成率及得分明顯提高。健康教育聯(lián)合藥物治療對(duì)改善新疆農(nóng)村地區(qū)少數(shù)民族血脂異常患者的血脂水平切實(shí)有效,適宜推廣應(yīng)用。
[Abstract]:Objective: to evaluate the effect of health education combined with drug therapy on the patients with dyslipidemia in Kazak and Uygur nationality in rural areas of Xinjiang. To provide a scientific basis for the treatment of dyslipidemia in rural ethnic minorities in Xinjiang. Methods: in this study, 18 natural villages were randomly divided into intervention village and control village by stratified cluster random sampling in Nalati Town, Yili County, Xinjiang, and Jiangbazhi Township, Kashgar County, Xinjiang. A baseline survey was carried out among Kazakh and Uygur residents aged 18 and above in the above villages, and the patients diagnosed as dyslipidemia in the investigated population were selected as the research objects. Questionnaire information, physical examination and blood sample collection were collected through household visits. The intervention group was treated with health education, such as reducing salt, low fat diet, eating more vegetables and simvastatin, while the control group did not take any measures. The patients were followed up for 2 years. The methods and contents of the outcome survey were the same as the baseline. Serum total cholesterol (TC), triglyceride (TG), low density lipoprotein cholesterol (LDL-C) and high density lipoprotein cholesterol (HDL-C) were detected by OLYMPUS 2007 automatic biochemical instrument. SPSS 17.0 software was used to carry out statistical analysis. The measurement data were described by X 鹵s. T test was used to compare the mean of the two groups, the repeated measurement data was analyzed by the analysis of variance of repeated measurements, and Pearson 蠂 2 test was used to compare the rate or composition ratio. The result is 1: 1. 784 subjects, 518 cases in the intervention group and 266 cases in the control group were selected. 94 cases were lost after 3 years follow-up, and the follow-up rate was 88.0%. There were 460 patients in the intervention group and 230 in the control group with a follow-up rate of 88. 8% and a follow-up rate of 86. 5% and 2. 2% respectively. After comprehensive intervention, the decrease of LDL-C of TGN in the intervention group was 2.80 and 12.12, respectively. The increase of HDL-C was 23.00. The difference was statistically significant compared with the control group. Compared with the baseline, the LDL-C level in the intervention group was decreased to 4.06 鹵0.94mmol / L, 2.03 鹵0.61mmol / L, P 0.05g / L increased by 1.23 鹵0.46mmol / L, 0.05g / L, respectively. The control rate of serum lipids in the intervention group was 38.70, which was higher than that in the control group (蠂 2, 62.407, P 0.01. 4). After comprehensive intervention, the average awareness rate of dyslipidemia in intervention group and control group was 26.2and 5.5, the average formation rate of belief was 35.1and 7.5, and the average rate of behavior formation was 12.9and 3.7.The difference was statistically significant (P 0.05). In the intervention group, the rate of knowledge awareness, belief formation and behavior formation in patients with dyslipidemia were significantly higher than those before intervention, and the differences were statistically significant (P 0.05). After comprehensive intervention, the scores of dyslipidemia in the intervention group and the control group were 1.39 鹵1.18, 1.39 鹵1.18, 0.82 鹵0.92, 0.11 鹵1.10 and 0.70 鹵0.96, respectively. The average total score was 6.50 鹵3.30 and 2.91 鹵2.31, respectively, and there was a difference between the two groups. Conclusion: the level of blood lipids in patients with dyslipidemia in the intervention group was improved by 3 years of health education combined with comprehensive intervention of drug therapy, and the improvement range was better than that of the control group. The control rate of 4 items of lipid level in the control group was obviously improved, and the rate of knowledge awareness was improved. Belief formation rate, behavior formation rate and score increased significantly. Health education combined with drug therapy is effective in improving the blood lipid level of ethnic minority patients with dyslipidemia in rural areas of Xinjiang, and is suitable for popularization and application.
【學(xué)位授予單位】：石河子大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2015
【分類號(hào)】：R589.2

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本文編號(hào)：2021689