發(fā)布時間：2018-05-17 11:17

  本文選題：艾滋病 + 抗病毒治療��； 參考：《中國公共衛(wèi)生》2017年01期

【摘要】：目的了解成年艾滋病抗病毒治療患者生存狀況及其影響因素,為改善艾滋病患者生存狀況提供參考依據。方法收集2006年9月—2010年9月在寧夏醫(yī)科大學總醫(yī)院接受抗病毒治療的152例≥18周歲成年艾滋病患者病歷資料,分析其在觀察期間的生存狀況,并采用多因素Cox比例風險回歸模型分析影響患者生存狀況的影響因素。結果 2015年9月30日隨訪截止時,152例成年艾滋病抗病毒治療患者中仍在治療102例(67.11%),失訪7例(4.61%),轉診10例(6.58%),停藥5例(3.29%),死亡28例(18.42%);28例死亡患者中,死于艾滋病者21例(75.00%),因其他因素致死者7例(25.00%);21例死于艾滋病患者中,抗病毒治療1年死亡11例(52.38%),2~3年死亡7例(33.33%),4~5年死亡3例(14.29%)。多因素Cox比例風險回歸分析結果顯示,年齡≥30歲、WHO臨床分期Ⅲ期以上、感染途徑為異性和同性性途徑感染是影響成年艾滋病抗病毒治療患者生存狀況的危險因素;CD4~+細胞計數200個/μL和抗病毒治療方案為≥2種抗菌藥物聯合治療是影響成年艾滋病抗病毒治療患者生存狀況的保護因素。結論年齡、CD4~+細胞計數、WHO臨床分期、抗病毒治療方案和感染途徑是成年艾滋病抗病毒治療患者生存狀況的主要影響因素。
[Abstract]:Objective to investigate the survival status and its influencing factors of adult AIDS patients treated with antiviral therapy, and to provide a reference for improving the survival status of AIDS patients. Methods from September 2006 to September 2010, 152 AIDS patients aged 18 years or older who received antiviral therapy in the General Hospital of Ningxia Medical University were collected, and their survival status during the observation period was analyzed. Multivariate Cox proportional risk regression model was used to analyze the influencing factors of patients' survival. Results at the end of follow-up on September 30, 2015, 102 out of 152 adult HIV / AIDS patients were still receiving treatment, 7 were missing, 10 were referred to 6.58, 5 were stopped taking medicine, 28 died from 18.42 and 28 died. Among the 21 cases who died of AIDS, 7 cases died of AIDS from 25.00% to 21 cases, 11 cases died of antiviral therapy in one year, 7 cases died in 2 ~ 3 years, 7 cases died from 33.33% in 4 ~ 5 years, 3 cases died 14.29%. Multivariate Cox proportional risk regression analysis showed that the age 鈮，

本文編號：1901158