終末糖基化產(chǎn)物在糖尿病勃起功能研究中的進(jìn)展
發(fā)布時(shí)間:2018-05-03 14:51
本文選題:終末糖基化產(chǎn)物 + 糖尿病; 參考:《中國老年學(xué)雜志》2017年20期
【摘要】:正勃起功能障礙(ED)是指在有性交意愿的情況下陰莖持續(xù)至少3個(gè)月不能達(dá)到和(或)維持充分的勃起狀態(tài)而獲得滿意的性生活~([1])。DM中ED患者為正常人群的3倍,且ED發(fā)生較正常人群早10~15年~([2~4])。DM陰莖組織中終末糖基化產(chǎn)物(AGEs)含量較正常人明顯增多~([5]),應(yīng)用AGEs抑制劑能改善DM大鼠勃起功能~([6])。本文對AGEs在DMED的發(fā)生、發(fā)展中
[Abstract]:Erectile dysfunction (EDD) is three times the number of patients with Ed who are not able to achieve and / or maintain a full erectile state for at least 3 months if they have sexual intercourse ([1] .DM). In addition, Ed occurred 10 ~ 15 years earlier than that in normal subjects ([2] 4). The end glycosylation products (ages) in the penile tissue of DM were significantly higher than those in normal controls ([5]). The application of AGEs inhibitor could improve erectile function in DM rats ([6]). This paper deals with the occurrence and development of AGEs in DMED.
【作者單位】: 佳木斯大學(xué)附屬第一醫(yī)院;佳木斯大學(xué)基礎(chǔ)醫(yī)學(xué)院;
【基金】:黑龍江省自然科學(xué)基金(No.H2015073) 佳木斯大學(xué)重點(diǎn)項(xiàng)目(No.Sz2013-005)
【分類號】:R587.2;R698
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