本文選題：冠心病　切入點(diǎn)：糖尿病　出處：《中國(guó)動(dòng)脈硬化雜志》2016年07期

【摘要】：目的探討糖尿病對(duì)經(jīng)皮冠狀動(dòng)脈介入治療(PCI)患者長(zhǎng)期預(yù)后的影響。方法連續(xù)入選2367例接受PCI的冠心病患者,根據(jù)有無(wú)糖尿病分為兩組:糖尿病組(719例)及非糖尿病組(1648例),通過(guò)COX回歸分析研究糖尿病對(duì)PCI患者長(zhǎng)期預(yù)后的影響。結(jié)果與非糖尿病組相比,糖尿病組男性更少,甘油三酯、N端B型利鈉肽原更高,高密度脂蛋白膽固醇更低,合并陳舊性心肌梗死、心功能不全、高血壓、腎功能不全、腦卒中的比例更高。糖尿病組患者冠狀動(dòng)脈3支病變比例、慢性閉塞比例、Gensini評(píng)分更高,平均支架個(gè)數(shù)更多,平均支架長(zhǎng)度更長(zhǎng)。術(shù)后隨訪顯示,兩組患者的全因死亡、主要不良心血管事件、心源性死亡、非致死性心肌梗死、非計(jì)劃再次血運(yùn)重建均無(wú)顯著差異。多因素COX回歸分析顯示,糖尿病與PCI患者長(zhǎng)期預(yù)后無(wú)顯著相關(guān)。結(jié)論合并糖尿病的PCI患者在臨床方面存在特殊性,但長(zhǎng)期預(yù)后并無(wú)顯著不良。
[Abstract]:Objective to investigate the effect of diabetes mellitus on the long-term prognosis of patients undergoing percutaneous coronary intervention (PCI). Methods 2367 consecutive patients with PCI were enrolled in this study. Patients with diabetes were divided into two groups: diabetic group (n = 719) and non-diabetic group (n = 1648). The effect of diabetes on long-term prognosis of patients with PCI was studied by COX regression analysis. The N-terminal B-type natriuretic peptide of triglyceride was higher, the high density lipoprotein cholesterol was lower, the patients with old myocardial infarction, heart failure, hypertension, renal insufficiency, The ratio of coronary artery disease to chronic occlusion was higher, the mean number of stents was higher, and the mean stent length was longer. There were no significant differences in major adverse cardiovascular events, cardiogenic death, non-fatal myocardial infarction and unplanned re-revascularization. Multivariate COX regression analysis showed that. Conclusion the long-term prognosis of PCI patients with diabetes mellitus is not significantly bad, but there is no significant correlation between the long-term prognosis of PCI patients with diabetes mellitus and the long-term prognosis of PCI patients.
【作者單位】： 中國(guó)醫(yī)科大學(xué)附屬盛京醫(yī)院心內(nèi)科;
【基金】：遼寧省科技廳社會(huì)發(fā)展攻關(guān)計(jì)劃(2011225020)
【分類號(hào)】：R587.1;R541.4

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