發(fā)布時間：2018-03-28 15:23

  本文選題：系統(tǒng)性紅斑狼瘡　切入點：侵襲性真菌病　出處：《中國皮膚性病學(xué)雜志》2017年09期

【摘要】：目的探討系統(tǒng)性紅斑狼瘡(SLE)并發(fā)侵襲性真菌病(IFD)的臨床特征。方法對2009年1月-2013年12月在本科住院的803例SLE患者臨床資料進(jìn)行分析,比較合并IFD與未合并IFD患者的臨床特點。結(jié)果 SLE并發(fā)IFD者27例,沒有確診的病例;從27例IFD患者中分離到33株真菌,其中白念珠菌30株(90.91%)、光滑念珠菌2株、克柔念珠菌1株,標(biāo)本分別來源于下呼吸道、消化道和泌尿道;抗真菌治療均有效。疑似感染癥狀,SLEDAI≥9,CRP≥0.8mg/d L為SLE合并IFD的獨立危險因素。結(jié)論本科SLE并發(fā)IFD的患者發(fā)生率為3.36%,致病菌以白念珠菌為主,氟康唑是有效的抗真菌治療藥物之一。
[Abstract]:Objective to investigate the clinical features of invasive mycosis (IFD) in patients with systemic lupus erythematosus (SLES). Methods the clinical data of 803 SLE patients hospitalized in our undergraduate course from January 2009 to December 2013 were analyzed. Results there were 27 cases of SLE complicated with IFD without definite diagnosis, 33 strains of fungi were isolated from 27 cases of IFD, including 30 strains of Candida albicans, 2 strains of Candida lucidum and 1 strain of Candida krsinensis. The specimens were derived from lower respiratory tract, digestive tract and urinary tract respectively. SLEDAI 鈮，

本文編號：1676898