本文選題：血尿酸　切入點：型糖尿病　出處：《中風(fēng)與神經(jīng)疾病雜志》2017年11期 　論文類型：期刊論文

【摘要】：目的探究血尿酸與2型糖尿病患者頸動脈粥樣硬化之間的關(guān)系。方法收集2017年1月~2017年6月符合納入試驗標(biāo)準(zhǔn)患者86例,采集患者入院時的性別、年齡、吸煙、飲酒、血尿酸、同型半胱氨酸、膽固醇、高密度脂蛋白、低密度脂蛋白及頸動脈內(nèi)膜中層厚度等數(shù)據(jù)。依據(jù)頸動脈內(nèi)膜中層厚度分為動脈粥樣硬化組與非動脈粥樣硬化組。結(jié)果通過動脈粥樣硬化組與非動脈粥樣硬化組相比較,動脈粥樣硬化組的體重指數(shù)(P0.001)、總膽固醇(P=0.01)、低密度脂蛋白(P=0.002)、血尿酸(P0.01)、同型半胱氨酸(P=0.03)比非動脈粥樣硬化組水平高,差異有統(tǒng)計學(xué)意義(P0.05)。多變量Logistic回歸分析顯示,體重指數(shù)、血尿酸水平、同型半胱氨酸是動脈粥樣硬化的獨立危險因素。結(jié)論在2型糖尿病患者中血尿酸水平與頸動脈粥樣硬化呈明顯相關(guān)性。
[Abstract]:Objective to investigate the relationship between serum uric acid and carotid atherosclerosis in patients with type 2 diabetes mellitus. Methods 86 patients who met the inclusion criteria from January 2017 to June 2017 were collected. Homocysteine, cholesterol, High density Lipoprotein, Low density lipoprotein (LDL) and intima-media thickness of carotid artery were divided into atherosclerosis group and non-atherosclerotic group according to carotid intima-media thickness. The body mass index (BMI) of atherosclerosis group was significantly higher than that of non-atherosclerotic group (P 0.001, total cholesterol, low density lipoprotein, low density lipoprotein, low density lipoprotein, blood uric acid, homocysteine), and the difference was statistically significant (P 0.05). Multivariate Logistic regression analysis showed that body mass index (BMI) was significantly higher than that in non-atherosclerotic group. Serum uric acid level, homocysteine is an independent risk factor for atherosclerosis. Conclusion there is a significant correlation between serum uric acid level and carotid atherosclerosis in patients with type 2 diabetes mellitus.
【作者單位】： 承德醫(yī)學(xué)院;寬城滿族自治縣醫(yī)院內(nèi)一科;保定市第一中心醫(yī)院神經(jīng)內(nèi)三科;
【分類號】：R587.2;R743

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1 任艷峰;血尿酸與糖尿病主要并發(fā)癥關(guān)系的研究[D];天津醫(yī)科大學(xué);2017年

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