本文選題：糖尿病　切入點：iMSDE　出處：《實用醫(yī)學雜志》2017年12期 　論文類型：期刊論文

【摘要】：目的:評價基于非對比增強磁共振血管成像(NCE-MRA)技術的優(yōu)化運動敏感驅動平衡(iMSDE)預備的平衡穩(wěn)態(tài)自由進動(bSSFP)序列在糖尿病患者下肢血管成像中的應用價值。方法:這項前瞻性研究招募了35例Ⅱ型糖尿病患者并在1.5TMR掃描儀上先后進行NCE-MRA和CE-MRA檢查;獲得的MIP圖像由兩位放射學醫(yī)師進行雙盲評分并以CE-MRA為參考標準檢測NCE-MRA對血管狹窄的診斷精度;兩者間血管診斷價值血管段比率的比較采用χ~2檢驗。結果:NCE-MRA在盆腔段血管中診斷價值血管段比率較CE-MRA降低。兩位醫(yī)師對NCE-MRA組圖像的敏感性、特異性、陽性預測值、陰性預測值以及NCE-MRA準確率分別為95%/87%、96%/95%、57%/72%、99%/99%、96%/95%(κ=0.76)。結論:此項基于NCE-MRA技術的iMSDE預備的bSSFP序列可有效的顯示糖尿病患者下肢動脈病變,并且具備不使用造影劑、掃描時間短優(yōu)點以及大腿及小腿段血管具備較好的診斷價值。
[Abstract]:Objective: to evaluate the application value of balanced steady-state free precession (bSSFPFP) sequence prepared by non-contrast enhanced magnetic resonance angiography (NCE-MRA) technique in patients with diabetes mellitus (DM). Methods:. The prospective study recruited 35 patients with type 2 diabetes and performed NCE-MRA and CE-MRA examinations on a 1.5T Mr scanner. The obtained MIP images were scored by two radiologists and the accuracy of NCE-MRA in the diagnosis of vascular stenosis was detected by using CE-MRA as the reference standard. 蠂 ~ 2 test was used to compare the ratio of diagnostic value of vascular segment between the two groups. Results the ratio of diagnostic value of vascular segment in the pelvic segment was lower than that of CE-MRA. The sensitivity, specificity and positive predictive value of the two physicians to the images of the NCE-MRA group were higher than those of the control group. The negative predictive value and the accuracy of NCE-MRA were 95 / 87 and 96 / 95, respectively. They were 57 / 72, and 99 / 99 / 99, 96 / 95, respectively. Conclusion: the bSSFP sequence prepared by iMSDE based on NCE-MRA technology can effectively display arterial lesions in the lower extremities of diabetic patients, and it has no contrast agent. The advantages of short scanning time and the blood vessels of thigh and leg have good diagnostic value.
【作者單位】： 南方醫(yī)科大學非直屬附屬廣東省第二人民醫(yī)院影像中心;新疆維吾爾自治區(qū)人民醫(yī)院影像中心;
【基金】：廣東省第二人民醫(yī)院青年基金項目(編號:YQ2015-015)
【分類號】：R445.2;R587.2

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