本文選題：哮喘　切入點(diǎn)：Astograph法　出處：《實(shí)用醫(yī)學(xué)雜志》2017年22期 　論文類型：期刊論文

【摘要】：目的評(píng)價(jià)Astograph法支氣管激發(fā)試驗(yàn)在診斷支氣管哮喘的應(yīng)用價(jià)值。方法選擇238例哮喘患者及489例非哮喘患者,完成Astograph法乙酰甲膽堿支氣管激發(fā)試驗(yàn),統(tǒng)計(jì)分析各指標(biāo)的差異,尋找具有診斷意義的指標(biāo)及臨界值。結(jié)果兩組Rrs cont、Grs cont均未見(jiàn)明顯差異。與非哮喘組比較,哮喘組Dmin、Cmin、PD15均減小(P0.01),SGrs、SGrs/Grs cont均增大(P0.01)。哮喘組SGrs與Dmin、Cmin、PD15相關(guān)(P=0.000;r=0.685,r=0.657,r=0.639),SGrs/Grs cont與Dmin、Cmin、PD15相關(guān)(P=0.000,r=0.775;r=0.740;r=0.708)。以Dmin診斷哮喘,臨界值2.71Unit,敏感性0.739,特異性0.551。以PD15診斷哮喘,臨界值4.8565 Unit,敏感性0.693,特異性0.684。結(jié)論 Astograph法支氣管激發(fā)試驗(yàn)對(duì)診斷哮喘具有重要作用,其中以Dmin≤2.71 Unit或PD15≤4.8565 Unit為陽(yáng)性標(biāo)準(zhǔn),對(duì)診斷哮喘有較好的敏感性及特異性。
[Abstract]:Objective to evaluate the value of Astograph bronchial provocation test in the diagnosis of bronchial asthma. Methods Astograph methacholine bronchial provocation test was completed in 238 asthmatic patients and 489 non-asthmatic patients. Results there was no significant difference between the two groups of Rrs contours Grs cont. Compared with the non-asthmatic group, the Dminn Cminn PD15 in asthma group decreased P0.01C / G _ rs cont increased (P 0.01). The correlation between SGrs and DminCminPD15 in asthma group was 0.685 ~ 0.657r0.657rr ~ (0.639) cont and DminCmin-PD15 respectively (P _ (0.0005) r ~ (0.740) ~ (0.708)) to diagnose Dmin asthma, and no significant difference was found between the two groups in the diagnosis of Dmin asthma, and there was no significant difference between the two groups in DminCmin-Grs cont and DminCmin-PD15 (P = 0.775r0.775r0.740r0.708) in order to diagnose the asthma of the asthmatic patients, there was no significant difference between the two groups in finding the diagnostic index and the critical value of the GRS. The results showed that there was no significant difference between the two groups. The critical value was 2.71 unit, sensitivity 0.739, specificity 0.551. The critical value of PD15 was 4.8565 unit, the sensitivity was 0.693, and the specificity was 0.684.Conclusion the bronchial provocation test with Astograph method has an important role in the diagnosis of asthma, in which Dmin 鈮，

本文編號(hào)：1610428