本文關(guān)鍵詞： 甲狀腺疾病 碘 甲狀腺功能亢進(jìn)癥 甲狀腺功能減退癥　出處：《中國(guó)全科醫(yī)學(xué)》2017年S2期 　論文類型：期刊論文

【摘要】：目的調(diào)查勝利油田中青年非妊娠女性碘營(yíng)養(yǎng)狀態(tài)和甲狀腺疾病,并分析二者的相互關(guān)系。方法以2012—2013年勝利油田中心醫(yī)院體檢的勝利油田中青年非妊娠女性為調(diào)查對(duì)象。進(jìn)行問(wèn)卷調(diào)查、體格檢查,并進(jìn)行尿碘檢測(cè)、甲狀腺功能、甲狀腺相關(guān)抗體和甲狀腺B超檢查。結(jié)果調(diào)查總?cè)巳耗虻庵形粩?shù)為113.4μg/L。其中甲狀腺疾病組413人,占44.36%,尿碘中位數(shù)112.7μg/L,與正常組比較差異無(wú)統(tǒng)計(jì)學(xué)意義(P0.05);不同甲狀腺疾病組尿碘水平比較,差異無(wú)統(tǒng)計(jì)學(xué)意義(P0.05),不同尿碘水平者三碘甲狀腺原氨酸(T_3)、甲狀腺素(T_4)、游離三碘甲狀腺原氨酸(FT_3)、游離甲狀腺素(FT_4)、促甲狀腺激素(TSH)水平比較,差異均無(wú)統(tǒng)計(jì)學(xué)意義(P0.05)。甲狀腺過(guò)氧化物酶抗體(TPOAb)陽(yáng)性組及甲狀腺球蛋白抗體(Tg Ab)陽(yáng)性組尿碘水平均明顯高于TPOAb陰性組及TgAb陰性組(P0.05)。多因素Logistic回歸分析結(jié)果顯示,年齡[OR=1.040,95%CI(1.009,1.071)]及甲狀腺抗體陽(yáng)性[OR=5.680,95%CI(3.864,8.349)]為中青年非妊娠女性甲狀腺疾病及功能異常的危險(xiǎn)因素(P0.05),而甲狀腺疾病發(fā)病與尿碘水平[OR=0.985,95%CI(0.822,1.182)]無(wú)相關(guān)性(P0.05)。結(jié)論勝利油田中青年非妊娠女性碘攝入充足,該人群甲狀腺疾病及功能異�？赡芘c年齡及甲狀腺抗體陽(yáng)性有關(guān),與碘營(yíng)養(yǎng)狀態(tài)無(wú)關(guān)。
[Abstract]:Objective to investigate iodine nutritional status and thyroid diseases of young and middle-aged non-pregnant women in Shengli Oilfield. Methods the young non-pregnant women in Shengli Oilfield from 2012-2013 were investigated by questionnaire, physical examination, urine iodine test and thyroid function. Results the median urinary iodine was 113.4 渭 g / L in the total population. The median of urinary iodine was 112.7 渭 g / L, which was not significantly different from that of the normal group (P 0.05), and the urinary iodine level of different thyroid diseases was higher than that of the normal group (P < 0.05). There was no significant difference (P 0.05). The levels of triiodothyronine (T3), thyroxine (T4), free triiodothyronine (FT3), free thyroxine (FT4), thyrotropin (TSH) in patients with different urinary iodine levels were compared. There was no significant difference in urinary iodine levels between the two groups. The levels of urinary iodine in the positive group and the positive group were significantly higher than those in the TPOAb negative group and the TgAb negative group (P 0.05). The results of multivariate Logistic regression analysis showed that the urinary iodine level of the positive group was significantly higher than that of the TgAb negative group. Age [ORV 1.040 ~ 95CII 1.009 + 1.071] and thyroid antibody positive (OR5.68095) were the risk factors of thyroid disease and abnormal function in young and middle-aged non-pregnant women (P 0.05), but there was no correlation between the incidence of thyroid disease and urinary iodine level [OR0.98595CI0.822221.182]. Conclusion the iodine intake of young and middle-aged non-pregnant women in Shengli Oilfield is adequate, and there is no correlation between the incidence of thyroid disease and urinary iodine level (OR0.98595CI0.8221.182). Conclusion the iodine intake of young and middle-aged non-pregnant women in Shengli oil field is adequate, and there is no significant correlation between the incidence of thyroid disease and urinary iodine level (OR0.98595CI0.8221.182). Thyroid disease and abnormal function may be related to age and thyroid antibody positive, but not to iodine nutritional status.
【作者單位】： 勝利油田中心醫(yī)院;
【分類號(hào)】：R581

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