本文關(guān)鍵詞： 視網(wǎng)膜病變 糖尿病 視網(wǎng)膜動脈 視網(wǎng)膜靜脈 血糖　出處：《中國現(xiàn)代醫(yī)學(xué)雜志》2017年21期 　論文類型：期刊論文

【摘要】：目的探討2型糖尿病T2(DM)視網(wǎng)膜動、靜脈直徑變化的影響因素。方法選取2015年6月-2015年12月該院收治的105例T2DM患者為研究對象,對所有患者的右眼進行彩色眼底照相,由系統(tǒng)半自動測量距離視乳頭中心1.0~1.5 PD范圍內(nèi)的動、靜脈直徑,采用多元線性回歸方法來分析其與性別、年齡、高血壓、空腹血糖(FBG)、糖化血紅蛋白(Hb A1c)、總?cè)８视?TG)、總膽固醇(TC)、DM病程及視網(wǎng)膜病變(DR)分期等的相關(guān)性。結(jié)果全部患者的視網(wǎng)膜動脈、靜脈的平均直徑分別為(52.07±7.89)和(85.92±8.87)μm。有47例(44.8%)合并DR。合并高血壓、DM病程≥10年的視網(wǎng)膜動脈直徑縮小,差異均有統(tǒng)計學(xué)意義(P0.05)。年齡65歲、FBG≥10.5 mmol/L、Hb A1c≥7.0%及DM病程≥10年的視網(wǎng)膜靜脈直徑增大,差異有統(tǒng)計學(xué)意義(P0.05)。隨著DM分期的進展,視網(wǎng)膜動脈直徑逐漸縮小,靜脈直徑逐漸增大,差異有統(tǒng)計學(xué)意義(P0.05)。多元線性回歸結(jié)果表明視網(wǎng)膜動脈直徑與年齡(b=-0.236,P0.05)、DM病程(b=-2.230,P0.05)和DR分期(b=-2.017,P0.05)存在線性關(guān)系。視網(wǎng)膜靜脈直徑與FBG(b=1.036,P0.05)、DR分期(b=2.256,P0.05)等存在線性關(guān)系。結(jié)論合并DR的DM患者容易出現(xiàn)視網(wǎng)膜動脈縮窄與靜脈擴張現(xiàn)象,且隨著DR病情的加重,視網(wǎng)膜動脈直徑越小,靜脈直徑越大。
[Abstract]:Objective to investigate the factors influencing the diameter of retinal artery and vein in type 2 diabetes mellitus (T2DM). Methods 105 cases of T2DM treated in our hospital from June 2015 to December 2015 were selected and their right eyes were examined by color fundus photography. The diameter of artery and vein in the range of 1.0 ~ 1.5 PD distance from the center of optic papilla was measured semi-automatically by the system. Multivariate linear regression method was used to analyze its relationship with sex, age, hypertension. The correlation of FBGG, HbA1cG, TGG, TCU DM course and DRN stage of retinopathy were observed. Results the retinal artery was found in all patients. The mean diameters of vein were 52.07 鹵7.89) and 85.92 鹵8.87 渭 m respectively. The diameter of retinal vein increased in 65 years old with FBG 鈮，

本文編號：1495502