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代謝綜合征對(duì)頸動(dòng)脈內(nèi)中膜厚度影響的性別差異研究

發(fā)布時(shí)間:2018-01-12 06:06

  本文關(guān)鍵詞:代謝綜合征對(duì)頸動(dòng)脈內(nèi)中膜厚度影響的性別差異研究 出處:《中國全科醫(yī)學(xué)》2016年20期  論文類型:期刊論文


  更多相關(guān)文章: 代謝綜合征 頸動(dòng)脈內(nèi)中膜厚度 性別


【摘要】:目的探討代謝綜合征(MS)對(duì)頸動(dòng)脈內(nèi)中膜厚度(CIMT)影響的性別差異。方法選取2013-10-08至2014-02-25于皖北煤電集團(tuán)總醫(yī)院參加體檢人群593例。受試者禁食8~12 h后,進(jìn)行常規(guī)體檢和生化指標(biāo)檢測(cè);由經(jīng)過培訓(xùn)的兩名專業(yè)醫(yī)師在短軸切面測(cè)量CIMT,取平均值。結(jié)果男性MS患病率為29.8%(105/353),女性MS患病率為24.6%(59/240),差異無統(tǒng)計(jì)學(xué)意義(χ~2=1.087,P0.05)。男性、絕經(jīng)前后女性中,不同MS組分?jǐn)?shù)者CIMT比較,差異均有統(tǒng)計(jì)學(xué)意義(F=12.240、8.850、9.510,P0.001)。男性、絕經(jīng)前后女性0、1項(xiàng)組分者CIMT比較,差異有統(tǒng)計(jì)學(xué)意義(F=8.890、8.620,P0.001),其中,男性、絕經(jīng)后女性0、1項(xiàng)組分者CIMT大于絕經(jīng)前女性,差異有統(tǒng)計(jì)學(xué)意義(P0.05)。男性、絕經(jīng)前后女性≥3項(xiàng)組分者CIMT比較,差異有統(tǒng)計(jì)學(xué)意義(F=0.670,P=0.002),其中,男性、絕經(jīng)后女性≥3項(xiàng)組分者CIMT大于絕經(jīng)前女性,絕經(jīng)后女性CIMT大于男性,差異有統(tǒng)計(jì)學(xué)意義(P0.05)。Logistic回歸分析顯示,MS是女性CIMT增厚的危險(xiǎn)因素〔OR=5.611,95%CI(1.398,22.632),P0.05〕,而未發(fā)現(xiàn)與男性CIMT增厚有關(guān)〔OR=1.091,95%CI(0.906,1.314),P0.05〕。結(jié)論 MS對(duì)CIMT的影響存在性別差異,MS對(duì)女性CIMT的影響更顯著。
[Abstract]:Objective to investigate the effect of metabolic syndrome (MS) on carotid intima-media thickness (IMT). Methods from 2013-10-08 to 2014-02-25, 593 subjects were enrolled in the physical examination in the General Hospital of North Anhui Coal and Power Group. The subjects were fasting for 812 hours. Routine physical examination and biochemical index test; CIMT was measured on the short axis section by two trained physicians. Results the prevalence of MS in men was 29.88 / 105 / 353). The prevalence rate of MS in female was 24.60.59 / 240%, and there was no significant difference (蠂 ~ (2 / 2) 1.087 / P 0.05) among male, premenopausal and postmenopausal women. The difference of CIMT in different MS groups was statistically significant (P < 0.05). There were significant differences in CIMT between male and postmenopausal women (P 0.001), and there were significant differences between male and postmenopausal women (P < 0.01). There was a significant difference in CIMT between one component (8.890) and 8.620 (P0.001). Among them, male, postmenopausal female were 0. The CIMT of one component was higher than that of premenopausal women, and the difference was statistically significant (P 0.05). The CIMT of male and female before and after menopause 鈮,

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