本文關(guān)鍵詞：初診2型糖尿病患者胰島素抵抗與腎素血管緊張素醛固酮系統(tǒng)的關(guān)系　出處：《實(shí)用醫(yī)學(xué)雜志》2016年20期 　論文類型：期刊論文

  更多相關(guān)文章： 糖尿病 型 胰島素抵抗 腎素血管緊張素醛固酮系統(tǒng)

【摘要】：目的:探討初診的2型糖尿病患者胰島素抵抗與腎素血管緊張素醛固酮系統(tǒng)(RASS)的關(guān)系,為糖尿病合并有高血壓病的患者提供最佳的治療方案。方法:初診的90例2型糖尿病患者根據(jù)性別分層后以有無高血壓病史分成合并組和非合并組,前者再根據(jù)服降壓藥的情況分成未服藥組、服鈣通道阻滯劑(CCB)組、服血管緊張素受體拮抗劑(ARB)組。結(jié)果:女性合并有高血壓病組IAI、腎素及血管緊張素Ⅱ水平高于非合并組。服降壓藥者血壓明顯較未用藥者低,女性組中服用ARB的收縮壓較服用CCB者更低。Pearson相關(guān)分析顯示女性組中HOMA-IR與血管緊張素Ⅱ及醛固酮的水平呈正相關(guān),IAI與血管緊張素Ⅱ及醛固酮的水平呈負(fù)相關(guān)。結(jié)論:在初診的2型糖尿病女性患者中RASS參與胰島素抵抗的發(fā)生發(fā)展,因此首選RASS拮抗劑有助于更好地控制血糖。
[Abstract]:Objective: to investigate the relationship between insulin resistance and renin angiotensin aldosterone system (RASS) in newly diagnosed type 2 diabetic patients. Methods: 90 newly diagnosed patients with type 2 diabetes were divided into two groups according to gender stratification according to the history of hypertension. The former was then divided into three groups according to the situation of taking antihypertensive drugs: no medication group, calcium channel blocker group and angiotensin receptor antagonist group. Results: women with hypertension had IAI. The levels of renin and angiotensin 鈪，

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