本文關(guān)鍵詞：低密度脂蛋白膽固醇與跟腱厚度相關(guān)性的初步臨床研究　出處：《中國(guó)循環(huán)雜志》2016年02期 　論文類型：期刊論文

  更多相關(guān)文章： 脂蛋白類 LDL 跟腱 黃瘤病 放射攝影術(shù)

【摘要】：目的:研究血清低密度脂蛋白膽固醇(LDL-C)水平與跟腱厚度(ATT)之間的相關(guān)性。方法:2014-03至2015-03期間收集18~75歲、血清LDL-C水平高于正常上限(≥3.37 mmol/L)的患者154例,根據(jù)《中國(guó)成人血脂異常防治指南(2007年)》,分為L(zhǎng)DL-C邊緣升高(3.37~4.12 mmol/L)組(n=50)和LDL-C升高(≥4.14 mmol/L)組(n=104);另以血清LDL-C水平正常(3.37 mmol/L)者作為對(duì)照組(n=51)。采用標(biāo)準(zhǔn)化的直接數(shù)字化X線攝影術(shù)測(cè)量三組受試者的ATT,進(jìn)行比較,并分析血清LDL-C水平與ATT之間的相關(guān)性。結(jié)果:LDL-C升高組的ATT平均值[(9.42±3.63)mm]高于LDL-C邊緣升高組[(8.24±1.73)mm]和對(duì)照組[(6.05±0.28)mm],三組受試者ATT間的差異均具有統(tǒng)計(jì)學(xué)意義(P均0.05)。線性相關(guān)分析顯示,血清LDL-C水平與ATT平均值的相關(guān)系數(shù)r=0.346(P0.001)。結(jié)論:本研究小樣本初步觀察發(fā)現(xiàn),血清LDL-C水平越高,ATT越厚,血清LDL-C水平與ATT呈正相關(guān),該現(xiàn)象及其意義有待大樣本多中心研究進(jìn)一步證實(shí)。
[Abstract]:Objective: To study the correlation between serum low density lipoprotein cholesterol (LDL-C) level and the thickness of Achilles tendon (ATT). Methods: 2014-03 and 2015-03 were collected during the 18~75 years of age, the serum level of LDL-C was higher than the normal limit (mmol/L = 3.37) of 154 cases of patients, according to the "China adult dyslipidemia prevention guide" (2007), divided into the edge of the LDL-C (3.37~4.12 mmol/L) group increased (n=50) and LDL-C (high rise more than 4.14 mmol/L (n=104 group)); the other to normal level of serum LDL-C (3.37 mmol/L) as control group (n=51). The ATT of three groups of subjects was measured by standardized direct digital radiography, and the correlation between serum LDL-C level and ATT was analyzed. Results: the mean value of ATT in LDL-C increased group [(9.42 + 3.63) mm] was higher than that in LDL-C marginal elevation Group [(8.24 + 1.73) mm] and control group [(6.05 + 0.28) mm], three groups of subjects had significant differences in ATT (P all 0.05). Linear correlation analysis showed that the correlation coefficient of serum LDL-C level and the mean value of ATT was r=0.346 (P0.001). Conclusion: the small sample preliminary observation shows that the higher serum LDL-C level and the thicker the ATT is, the positive correlation is found between serum LDL-C level and ATT. This phenomenon and its significance need further confirmation by large sample and multicenter study.
【作者單位】： 海南省農(nóng)墾三亞醫(yī)院心內(nèi)科;廣州醫(yī)科大學(xué)研究生學(xué)院;海南省農(nóng)墾三亞醫(yī)院放射科;海南省農(nóng)墾三亞醫(yī)院檢驗(yàn)科;
【基金】：海南省醫(yī)藥衛(wèi)生科研項(xiàng)目(1421320.24A1005)
【分類號(hào)】：R589.2
【正文快照】： 血清膽固醇水平升高會(huì)導(dǎo)致皮膚和肌腱黃色korotkoff第Ⅰ音和第Ⅴ音作為收縮壓(SBP)、舒張瘤的出現(xiàn)[1],這種表現(xiàn)在家族性高膽固醇血癥(FH)壓(DBP),間隔1~2 min重復(fù)測(cè)量,取2次讀數(shù)的患者中尤為明顯[2-4]。跟腱作為全身最厚最強(qiáng)壯的平均值記錄。如果SBP或DBP的2次讀數(shù)相差5肌腱[5，

本文編號(hào)：1343834