本文選題：腎結(jié)石 + 尿路感染��； 參考：《現(xiàn)代泌尿外科雜志》2017年10期

【摘要】：目的探討廣州醫(yī)科大學(xué)附屬第一醫(yī)院泌尿外科腎結(jié)石合并尿路感染的感染率、病原菌分布及耐藥性,為臨床合理用藥提供依據(jù)。方法收集廣州醫(yī)科大學(xué)附屬第一醫(yī)院泌尿外科2009年1月至2016年12月腎結(jié)石合患者中段尿培養(yǎng)資料,統(tǒng)計(jì)并分析菌譜和耐藥性的變化。結(jié)果從14 063份腎結(jié)石患者中段尿標(biāo)本中分離致病菌3 280株,陽(yáng)性率為23.3%。腎結(jié)石合并尿路感染主要致病菌為大腸埃希菌(47.13%),肺炎克雷伯菌(8.35%)、糞腸球菌(8.14%)、奇異變形桿菌(7.10%)和銅綠假單胞菌(4.97%)。大腸埃希菌、肺炎克雷伯菌、銅綠假單胞菌和奇異變形桿菌對(duì)阿米卡星、哌拉西林/他唑巴坦、亞胺培南耐藥率≤10%,鮑曼不動(dòng)桿菌對(duì)頭孢吡肟、亞胺培南耐藥率≥20.00%。糞腸球菌、屎腸球菌和凝固酶陰性葡萄球菌對(duì)萬(wàn)古霉素和替考拉寧的敏感率為100%。結(jié)論大腸埃希菌是腎結(jié)石患者合并尿路感染的主要致病菌,對(duì)青霉素類(lèi)、喹諾酮類(lèi)、第3代頭孢菌素、磺胺類(lèi)抗菌藥物耐藥率較高;對(duì)阿米卡星、β-內(nèi)酰胺酶抑制劑復(fù)合制劑、亞胺培南等藥物敏感。
[Abstract]:Objective to investigate the infection rate, distribution and drug resistance of renal calculi complicated with urinary tract infection in the first affiliated Hospital of Guangzhou Medical University. Methods the data of urinary culture from January 2009 to December 2016 in urology department of the first affiliated Hospital of Guangzhou Medical University were collected and the changes of bacterial spectrum and drug resistance were analyzed. Results 3 280 strains of pathogenic bacteria were isolated from 14 063 urine samples from patients with renal calculi, the positive rate was 23. 3%. The main pathogens of renal calculi with urinary tract infection were Escherichia coli (47.13%), Klebsiella pneumoniae (8.35%), Enterococcus faecalis (8.14%), Proteus mirabilis (7.10%) and Pseudomonas aeruginosa (4.97%). Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa and Proteus mirabilis were resistant to amikacin, piperacillin / tazobactam, imipenem 鈮，

本文編號(hào)：2076901