非嵌合型Klinefelter綜合征患者顯微取精術(shù)研究進(jìn)展
發(fā)布時(shí)間:2018-06-26 18:24
本文選題:Klinefelter綜合征 + 非梗阻性無(wú)精子癥。 參考:《中華男科學(xué)雜志》2017年09期
【摘要】:Klinefelter綜合征(KS)是男性最常見(jiàn)的性染色體異常疾病,第二性征發(fā)育遲滯或不發(fā)育及不育是其最常見(jiàn)臨床表現(xiàn)。隨著現(xiàn)代輔助生殖技術(shù)的發(fā)展,KS患者擁有自己遺傳學(xué)意義后代成為可能。顯微睪丸取精術(shù)(m TESE)是公認(rèn)的最佳取精術(shù)式,本文就其預(yù)測(cè)指標(biāo)、取精成功率、手術(shù)方法、術(shù)后并發(fā)癥、術(shù)前性激素替代治療及術(shù)后睪酮下降等問(wèn)題進(jìn)行綜述。
[Abstract]:Klinefelter syndrome (KS) is the most common sex chromosome abnormality in males, and the second sexual sign is the most common clinical manifestation. With the development of modern assisted reproductive technology, it is possible for KS patients to have their own offspring with genetic significance. Microtesticular spermatoplasty (mTESE) is considered as the best method for spermaticotomy. This article reviews its prediction index, successful rate of spermatogenesis, operative methods, postoperative complications, preoperative hormone replacement therapy and postoperative testosterone decline.
【作者單位】: 華中科技大學(xué)同濟(jì)醫(yī)學(xué)院附屬同濟(jì)醫(yī)院泌尿外科;華中科技大學(xué)同濟(jì)醫(yī)學(xué)院附屬同濟(jì)醫(yī)院泌尿外科研究所;
【分類號(hào)】:R698.2
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本文編號(hào):2070994
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