本文關(guān)鍵詞：自發(fā)性腦出血急性期血腫擴(kuò)大相關(guān)危險(xiǎn)因素，由筆耕文化傳播整理發(fā)布。

自發(fā)性腦出血急性期血腫擴(kuò)大相關(guān)危險(xiǎn)因素

Risk factors of hematoma enlargement in spontaneous intracerebral hemorrhage at acute stage

[1] [2] [3] [4]

WU Yan;REN Ming-shan;CHENG Zhao-zhao;（Department of neurology,Affiliated provincial hospital of anhui medical university; Hefei 230001, China）

安徽醫(yī)科大學(xué)附屬省立醫(yī)院神經(jīng)內(nèi)科,合肥230000

文章摘要：目的探討自發(fā)性腦出血急性期血腫擴(kuò)大的相關(guān)危險(xiǎn)因素。方法收集97例自發(fā)性腦出血患者的臨床資料。于發(fā)病6 h及48 h時對患者進(jìn)行頭顱CT檢查。分析血腫擴(kuò)大的相關(guān)危險(xiǎn)因素。結(jié)果根據(jù)5點(diǎn)分級標(biāo)準(zhǔn),規(guī)則血腫48例（49.48%）,不規(guī)則血腫49例（50.52%）;均質(zhì)血腫62例（63.92%）,不均質(zhì)血腫35例（36.08%）。27例（27.84%）患者發(fā)生血腫擴(kuò)大（血腫擴(kuò)大組）,70例（72.16%）患者血腫無進(jìn)展（血腫未擴(kuò)大組）。與血腫未擴(kuò)大組比較,血腫擴(kuò)大組患者年齡、血腫量、入院時及入院3 h的收縮壓,以及高血壓病、糖尿病、抗凝治療史、吸煙史、不規(guī)則血腫、不均質(zhì)血腫的比率均顯著增高,GCS顯著降低（P〈0.05∽0.01）。多因素Logistic分析發(fā)現(xiàn),不均質(zhì)血腫和入院3 h收縮壓升高是血腫擴(kuò)大的獨(dú)立危險(xiǎn)因素（OR=47.377,95%CI：7.827∽286.789,P〈0.001;OR=20.969,95%CI：3.826∽114.923,P〈0.001）。結(jié)論不均質(zhì)血腫和入院3 h SBP升高是血腫擴(kuò)大的獨(dú)立危險(xiǎn)因素。

Abstr：Objective To investigate the risk factors of hematoma enlargement in spontaneous intracerebral hemorrhage at acute stage. Methods The clinical data of 97 spontaneous intracerebral hemorrhage patients were collected. The brain CT was checked at 6 h and 48 h after noset. The related risk factors of hematoma enlargement were analyzed. Results According to 5-point categorical scales,regular hematomata was in 48 cases（ 49. 48%）,and irregular hematomata was in 49 caese（ 50. 52%）; homogeneous hematomata was in 62 cases（ 63. 92%）,and heterogeneous hematomata was in 35 cases（ 36. 08%）. Twenty-seven cases（ 27. 84%） had hematoma enlargement（ hematoma enlargement group）,and 70 cases（ 72. 16%） didn＇t have hematoma enlargement（ no-hematoma enlargement group）. Compared with no-hematoma enlargement group,age,hematoma volume,systolic pressure at admission and 3 h after admission,and the rates of hypertension,diabetic,anticoagulant treatment history,smoke,irregular hematomata,heterogeneous hematomata in hematoma enlargement group were significantly increased,GCS was significantly decreased（ P〈0. 05- 0. 01）. Multivariate Logistic analysis showed heterogeneous hematomata and systolic pressure at 3 h after admission were independent risk factors of hematoma enlargement（ OR = 47. 377,95%CI： 7. 827- 286. 789,P〈0. 001; OR = 20. 969,95% CI： 3. 826- 114. 923,P〈0. 001）. Conclusion Heterogeneous hematomata and systolic pressure at 3 h after admission are independent risk factors of hematoma enlargement.

文章關(guān)鍵詞：

Keyword：:spontaneous intracerebral hemorrhage hematoma further expand risk factors

課題項(xiàng)目：安徽省衛(wèi)生廳科研課題（13ZC016）

作者信息：會員可見

  本文關(guān)鍵詞：自發(fā)性腦出血急性期血腫擴(kuò)大相關(guān)危險(xiǎn)因素，由筆耕文化傳播整理發(fā)布。