【摘要】：目的:研究黃體血流分級(jí)對(duì)于未破裂型輸卵管妊娠保守治療的影響,為患者臨床治療提供參考。方法:回顧性分析2013年6月至2016年12月在西安交通大學(xué)第一附屬醫(yī)院婦產(chǎn)科就診的未破裂型輸卵管妊娠保守治療132例患者的臨床資料,根據(jù)妊娠黃體的血流分級(jí)分為0級(jí)組(31例)、1級(jí)組(34例)、2級(jí)組(38例)、3級(jí)組(29例)。比較各組患者治療后血β-人絨毛膜促性腺激素(β-HCG)下降、包塊縮小情況及療效。結(jié)果:(1)黃體血流分級(jí)中0級(jí)組患者治療后不同時(shí)間點(diǎn)血β-HCG水平均最低、下降至正常所需時(shí)間最短(14.39±2.67天),保守治療后不同時(shí)間點(diǎn)包塊直徑均最小,包塊完全消失所需時(shí)間最短(13.30±2.24天);3級(jí)組患者血β-HCG水平均最高,下降至正常所需時(shí)間最長(zhǎng)(27.04±4.56天),保守治療后不同時(shí)間點(diǎn)包塊直徑均最大,包塊完全消失所需時(shí)間最長(zhǎng)(24.11±3.44天),4組間比較,差異有統(tǒng)計(jì)學(xué)意義(P0.05)。(2)黃體血流分級(jí)中0級(jí)組患者治療有效率最高(90.32%),3級(jí)組最低(72.41%),4組間比較,差異有統(tǒng)計(jì)學(xué)意義(P0.05)。(3)所有患者中不良反應(yīng)包括血清轉(zhuǎn)氨酶升高5例、胃腸道反應(yīng)9例、困乏嗜睡4例,4組間不良反應(yīng)比較經(jīng)Fisher確切概率法檢驗(yàn),差異無(wú)統(tǒng)計(jì)學(xué)意義(P0.05),保守治療結(jié)束后患者不良反應(yīng)均消失。結(jié)論:黃體血流分級(jí)對(duì)未破裂型輸卵管妊娠保守治療有影響,血流分級(jí)越高,治療所需時(shí)間越長(zhǎng),療效越差。
[Abstract]:Objective: to study the effect of luteal blood flow grading on conservative treatment of unruptured tubal pregnancy. Methods: the clinical data of 132 cases of unruptured tubal pregnancy treated conservatively from June 2013 to December 2016 in the department of gynaecology and obstetrics of the first affiliated Hospital of Xi'an Jiaotong University were retrospectively analyzed. According to the blood flow grade of corpus luteum, they were divided into three groups: grade 0 (n = 31), grade 1 (n = 34), grade 2 (n = 38) and grade 3 (n = 29). The serum 尾-human chorionic gonadotropin (尾-HCG), mass reduction and curative effect were compared in each group after treatment. Results: (1) the level of 尾-HCG in group 0 was the lowest at different time points after treatment, and the shortest time was required to decrease to normal (14.39 鹵2.67 days), and the diameter of mass was the smallest at different time points after conservative treatment. It took the shortest time for the mass to disappear completely (13.30 鹵2.24 days). The level of serum 尾-HCG was the highest in grade 3 patients, and the longest time was required to decrease to normal (27.04 鹵4.56 days). The diameter of the masses was the largest at different time points after conservative treatment, and the longest time was required for the complete disappearance of the masses (24.11 鹵3.44 days). 4 the difference between groups was statistically significant (P0.05). (2). The effective rate of treatment was the highest in grade 0 group (90.32%), the lowest in grade 3 group (72.41%), and among the four groups, the treatment efficiency was the highest in grade 0 group (90.32%), the lowest in grade 3 group (72.41%). The difference was statistically significant (P0.05). (3) in all patients, including elevated serum transaminase (5 cases), gastrointestinal reactions (9 cases) and sleepiness (4 cases). The adverse reactions among the 4 groups were tested by Fisher's exact probability method. There was no significant difference between the two groups (P0.05). The adverse reactions disappeared after conservative treatment. Conclusion: luteal blood flow grading has an effect on conservative treatment of unruptured tubal pregnancy. The higher the blood flow grade, the longer the treatment time and the worse the curative effect.
【作者單位】： 西安交通大學(xué)第一附屬醫(yī)院;
【分類(lèi)號(hào)】：R714.221

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