【摘要】：目的:探討子宮內膜癌合并結直腸癌雙原發(fā)癌患者的臨床表現(xiàn)、治療方法及其預后,并分析與Lynch綜合征關系。方法:回顧性分析中國醫(yī)學科學院腫瘤醫(yī)院34例子宮內膜癌合并結直腸癌雙原發(fā)癌患者的臨床病理資料。結果:34例患者的中位發(fā)病年齡為51.5(39~76)歲,64.7%(22/34)有腫瘤家族史,子宮內膜樣腺癌占79.4%(27/34)。34例中33例雙原發(fā)癌患者行手術治療,19例子宮內膜癌、17例結直腸癌術后行放化療。2年生存率為84.3%,5年生存率為63.1%。結論:子宮內膜癌合并結直腸癌雙原發(fā)癌患者多具有腫瘤家族史、發(fā)病年齡早、預后與散發(fā)型結直腸癌相近,部分患者符合Lynch綜合征。
[Abstract]:Aim: to investigate the clinical manifestation, treatment and prognosis of patients with endometrial carcinoma complicated with colorectal cancer and to analyze the relationship between the clinical manifestation and Lynch syndrome. Methods: the clinical and pathological data of 34 patients with endometrial carcinoma complicated with double primary carcinoma of colorectal cancer were retrospectively analyzed in the Cancer Hospital, Chinese Academy of Medical Sciences (CAS). Results: the median age of onset was 51.5 (39 / 76) years old, 64.7% (22 / 34) had family history of tumor and 79.4% (27 / 34) had endometrioid adenocarcinoma. 19 cases of endometrial carcinoma and 17 cases of colorectal cancer were treated with radiotherapy and chemotherapy. The 2-year survival rate was 84.3% and the 5-year survival rate was 63.1%. Conclusion: most of the patients with endometrial carcinoma complicated with colorectal cancer have family history, early onset age, similar prognosis and sporadic colorectal cancer. Some of the patients are in accordance with Lynch syndrome.
【作者單位】： 中國醫(yī)學科學院腫瘤醫(yī)院婦瘤科;北京協(xié)和醫(yī)學院;
【分類號】：R737.33;R735.34

【共引文獻】

相關期刊論文 前9條

1 金丹;朱小寶;田小林;;Ⅱ型糖尿病與結直腸癌相關研究進展[J];結直腸肛門外科;2014年05期

2 張勤波;;經(jīng)陰道超聲檢查在卵巢癌篩查中的應用進展[J];內科;2014年04期

3 駱秀婷;許岸高;陳利強;林克宣;;結直腸腫瘤合并糖調節(jié)受損患者的分析[J];中國醫(yī)藥指南;2013年32期

4 李莎;劉蕊;;2型糖尿病患者發(fā)生結直腸癌影響因素的研究進展[J];中國老年學雜志;2014年04期

5 Chun-Xiao Xu;Hong-Hong Zhu;Yi-Min Zhu;;Diabetes and cancer: Associations, mechanisms, and implications for medical practice[J];World Journal of Diabetes;2014年03期

6 曹宏;黃德芳;孫道崎;劉超;;糖尿病與結直腸癌危險關系的分析[J];江蘇醫(yī)藥;2014年11期

7 Ma，

本文編號：2457334