【摘要】：目的：通過對我院圍產期心肌病病例資料統(tǒng)計，總結該病的發(fā)病特點、臨床特征及預后，提高對圍產期心肌病的認識。 方法：搜集2008年11月-2013年11月于吉林大學第二醫(yī)院住院的37例圍產期心肌病病歷資料，采用回顧性分析的方法，分析其一般臨床資料、癥狀和體征、相關輔助檢查（如:心電圖、心臟彩超、實驗室檢查等）、診治及預后等。 結果：1.本組患者初產婦21例（56.7%），經產婦16例（43.3%）.農村患者26例(70.2%)，，城鎮(zhèn)患者11例(29.8%)。 2.圍產期心肌病主要臨床表現(xiàn)為勞累性胸悶、氣短（28/37）、夜間陣發(fā)性呼吸困難（20/37）、心悸(18/37).且入院患者心功能絕大部分為III-IV級（34/37），心功能II級僅3例。 3.圍產期心肌病患者低蛋白血癥發(fā)病率較高（14/37），且D-二聚體升高明顯，監(jiān)測D-二聚體18例，其中14例1000μg/L 4.本組患者37例，死亡4例（10.8%），復查心臟彩超17例，EF恢復正常12例。 結論：1.本組圍產期心肌病初產婦發(fā)病率相對較高（56.7%）與國外流行病學結果不符。 2．勞累性胸悶、氣短、心悸及夜間陣發(fā)性呼吸困難為圍產期心肌病的常見癥狀，圍產期女性出現(xiàn)上述癥狀應考慮圍產期心肌病，提高早期診斷，降低漏診率。 3．圍產期心肌病患者易出現(xiàn)低蛋白血癥及栓塞。 4.圍產期心肌病發(fā)病率雖然較低，但死亡率較高（本組患者死亡率10.8%），經系統(tǒng)內科治療后，其預后較好，應提高早期診斷及治療，降低死亡率。
[Abstract]:Objective: to summarize the characteristics, clinical features and prognosis of perinatal cardiomyopathy in our hospital, and to improve the understanding of perinatal cardiomyopathy. Methods: 37 cases of perinatal cardiomyopathy hospitalized in the second Hospital of Jilin University from November 2008 to November 2013 were collected. The general clinical data, symptoms and signs were analyzed by retrospective analysis. Related auxiliary examination (e. G. Electrocardiogram, echocardiography, laboratory examination, etc.), diagnosis, treatment and prognosis. Results: 1. 21 cases (56.7%) were primipara, 16 cases (43.3%) were menopausal. There were 26 cases (70.2%) in rural areas and 11 cases (29.8%) in towns. 2. The main clinical manifestations of perinatal cardiomyopathy are tiring chest tightness, shortness of breath (28 / 37), nocturnal paroxysmal dyspnea (20 / 37), palpitation (18 / 37). Cardiac function was mostly III-IV grade (34 / 37) and cardiac function II grade was only 3 cases. 3. The incidence of hypoproteinemia in perinatal cardiomyopathy patients was high (14 / 37), and the level of D- dimer was significantly increased. 18 cases of D- dimer were monitored, of which 14 cases were 1000 渭 g / L ~ (4). Of the 37 patients, 4 died (10.8%), 17 were examined by echocardiography, 12 EF returned to normal. Conclusion: 1. The incidence of perinatal cardiomyopathy was relatively high (56.7%). 2. Tired chest tightness, shortness of breath, palpitation and nocturnal paroxysmal dyspnea are common symptoms of perinatal cardiomyopathy. Perinatal women should consider perinatal cardiomyopathy to improve early diagnosis and reduce the rate of missed diagnosis. 3. Perinatal cardiomyopathy patients are prone to hypoproteinemia and embolism. 4. Although the incidence of perinatal cardiomyopathy is low, the mortality rate is higher (mortality rate is 10.8%). After systemic medical treatment, its prognosis is better, so the early diagnosis and treatment should be improved and the mortality rate should be reduced.
【學位授予單位】：吉林大學
【學位級別】：碩士
【學位授予年份】：2014
【分類號】：R714.7

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