【摘要】：目的:探討稽留流產(chǎn)發(fā)生的高危因素。方法:通過病例-對照回顧性研究,收集稽留流產(chǎn)病例1 945例,同時(shí)與1 874例因非意愿妊娠20周內(nèi)的單活胎要求終止妊娠者(包括妊娠12周自愿要求終止妊娠者以及妊娠12~20周內(nèi)因內(nèi)外科因素不宜妊娠者)的病例資料進(jìn)行對比。分析與稽留流產(chǎn)發(fā)病相關(guān)的高危因素及環(huán)境等因素在稽留流產(chǎn)中可能產(chǎn)生的影響。結(jié)果:1Logistic多因素回歸分析顯示,與1 945例稽留流產(chǎn)發(fā)病正相關(guān)的危險(xiǎn)因素包括:室外職業(yè)者(OR=1.777,95%CI=1.538~2.052),初產(chǎn)婦(OR=2.305,95%CI=2.013~2.638),自然流產(chǎn)史(OR=2.359,95%CI=1.703~3.268),貧血(OR=5.498,95%CI=2.243~13.473),乙肝病毒攜帶者(OR=8.126,95%CI=4.688~14.084);與稽留流產(chǎn)發(fā)病負(fù)相關(guān)的危險(xiǎn)因素為人工流產(chǎn)≥3次(OR=0.726,95%CI=0.573~0.920)。2稽留流產(chǎn)獨(dú)立因素構(gòu)成變化顯示,環(huán)境因素及一些未知因素等構(gòu)成比升高(P0.05),與稽留流產(chǎn)發(fā)病數(shù)增加有關(guān)。結(jié)論:室外職業(yè)者、初產(chǎn)婦、自然流產(chǎn)病史、貧血和乙肝病毒攜帶者是稽留流產(chǎn)發(fā)生的獨(dú)立危險(xiǎn)因素,其中環(huán)境因素及一些未知因素的構(gòu)成比隨稽留流產(chǎn)發(fā)病數(shù)增加而升高。初步推論:基因、生育史、合并癥不能解釋稽留流產(chǎn)發(fā)病數(shù)的升高,而環(huán)境因素和一些未知因素可能是稽留流產(chǎn)病例數(shù)升高的重要原因之一。
[Abstract]:Objective: to explore the high risk factors of missed abortion. Methods: a retrospective case-control study was conducted to collect 1 945 cases of missed abortion. At the same time, the data of 1 874 cases of single live pregnancy requesting termination of pregnancy within 20 weeks of unwanted pregnancy (including those who voluntarily requested termination of pregnancy at 12 weeks of pregnancy and those who were not suitable for pregnancy due to internal and surgical factors within 20 weeks of gestation) were compared. To analyze the influence of high risk factors and environmental factors related to the incidence of missed abortion in missed abortion. Results: 1Logistic multivariate regression analysis showed that the risk factors associated with 1 945 cases of missed abortion were: outdoor occupational group (OR=1.777,95%CI=1.538~2.052), primipara (OR=2.305,95%CI=2.013~2.638), and the risk factors were: outdoor occupation (OR=1.777,95%CI=1.538~2.052), primipara (OR=2.305,95%CI=2.013~2.638). History of spontaneous abortion (OR=2.359,95%CI=1.703~3.268), anemia (OR=5.498,95%CI=2.243~13.473), hepatitis B virus carriers (OR=8.126,95%CI=4.688~14.084); The risk factors negatively correlated with the incidence of missed abortion were induced abortion 鈮，

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