【摘要】：目的:系統(tǒng)評價CZF超聲波婦科治療儀治療慢性宮頸炎的臨床療效。方法:計算機檢索Medline、Embase、Pub Med、中國生物醫(yī)學(xué)文獻(xiàn)數(shù)據(jù)庫(CBM)、維普中文科技期刊全文數(shù)據(jù)庫(VIP)、中國知識資源總庫(CNKI)、萬方數(shù)字化期刊全文數(shù)據(jù)庫(WF),查找以CZF超聲波婦科治療儀治療慢性宮頸炎的隨機對照試驗(randomized controlled trials,RCTs)或?qū)φ赵囼?對納入的研究進(jìn)行質(zhì)量評價,采用Rev Man5.2軟件進(jìn)行Meta分析。結(jié)果:共納入9項RCTs,共4 336例患者(治療組2 890例患者,對照組1 446例患者)。Meta分析結(jié)果顯示,治療組總有效率較對照組好(RR=1.08,95%CI=1.04~1.13,P=0.000),針對于慢性宮頸炎的具體分型,治療組治療輕度慢性宮頸炎的有效率與對照組無明顯統(tǒng)計學(xué)差異(RR=1.00,95%CI=0.99~1.02,P=0.72),但在治療中度、重度慢性宮頸炎而言,治療組有效率則要明顯優(yōu)于對照組(RR=1.07,95%CI=1.01~1.14,P=0.02)和(RR=1.24,95%CI=1.09~1.42,P=0.001)。治療組治療后陰道排液、陰道出血、宮頸結(jié)痂及瘢痕形成等的發(fā)生例數(shù)較對照組少,陰道排液(RR=0.25,95%CI=0.11~0.56,P=0.000);陰道出血(RR=0.14,95%CI=0.08~0.25,P=0.000);宮頸結(jié)痂(RR=0.01,95%CI=0.00~0.07,P=0.000);宮頸瘢痕形成(RR=0.01,95%CI=0.00~0.02,P=0.000)。結(jié)論:CZF超聲波婦科治療儀治療慢性宮頸炎較微波治療療效好,且可以減少治療后的不良反應(yīng)及后遺癥。
[Abstract]:Objective: to evaluate the clinical effect of CZF ultrasonic gynecological therapy instrument on chronic cervicitis. Methods: Medline,Embase,Pub Med, Chinese biomedical literature database (CBM), Weipu full text database of Chinese scientific and technological journals (VIP), Chinese knowledge resource database (CNKI), Wanfang digital full text journal database (WF), A randomized controlled trial (randomized controlled trials,RCTs) or a controlled trial with CZF ultrasonic gynecologic therapeutic instrument for the treatment of chronic cervicitis was found. The quality of the included studies was evaluated and the Meta analysis was carried out with Rev Man5.2 software. Results: a total of 4 336 patients (2 890 cases in the treatment group and 1 446 cases in the control group) were included in 9 items of RCTs,. The results of). Meta analysis showed that the total effective rate of the treatment group was better than that of the control group (RR=1.08,95%CI=1.04~1.13,P=0.000). According to the specific classification of chronic cervicitis, the effective rate of treating mild chronic cervicitis in the treatment group was not significantly different from that in the control group (RR=1.00,95%CI=0.99~1.02,P=0.72), but in the treatment of moderate and severe chronic cervicitis, The effective rate of the treatment group was significantly better than that of the control group (RR=1.07,95%CI=1.01~1.14,P=0.02) and (RR=1.24,95%CI=1.09~1.42,P=0.001). There were fewer cases of vaginal effusion, vaginal bleeding, cervical crusts and scar formation after treatment in the treatment group than in the control group. Vaginal effusion (RR=0.25,95%CI=0.11~0.56,P=0.000), vaginal bleeding (RR=0.14,95%CI=0.08~0.25,P=0.000), and so on were less in the treatment group than in the control group. Cervical scab (RR=0.01,95%CI=0.00~0.07,P=0.000); cervix scar formation (RR=0.01,95%CI=0.00~0.02,P=0.000). Conclusion: CZF ultrasonic gynecologic therapeutic instrument is more effective than microwave in the treatment of chronic cervicitis, and can reduce the adverse reactions and sequelae after treatment.
【作者單位】： 重慶醫(yī)科大學(xué)生物醫(yī)學(xué)工程學(xué)院省部共建國家重點實驗室培育基地—重慶市超聲醫(yī)學(xué)工程重點實驗室重慶市生物醫(yī)學(xué)工程學(xué)重點實驗室;中國人民解放軍總醫(yī)院超聲科;
【基金】：十二·五科技支撐計劃資助項目(編號:2011BAI14B01) 國家科技部973計劃資助項目(編號:2011CB707900)
【分類號】：R711.32

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