發(fā)布時(shí)間：2018-10-16 09:48

【摘要】：目的探討宮頸鱗癌血清鱗癌相關(guān)抗原(SCC-Ag)及糖類抗原125(CA125)水平與臨床病理參數(shù)的相關(guān)性。方法回顧性分析338例Ⅰ~Ⅳ期宮頸鱗癌患者的血清SCC-Ag及CA125水平,并對207例手術(shù)患者臨床病理參數(shù)進(jìn)行分析,探討SCC-Ag及CA125表達(dá)水平與患者臨床分期及病理參數(shù)之間的關(guān)系。結(jié)果 338例宮頸鱗癌患者中隨著臨床分期進(jìn)展,SCC-Ag水平明顯升高(P0.05),對207例手術(shù)患者中臨床病理參數(shù)進(jìn)行分析,發(fā)現(xiàn)SCC-Ag隨著腫瘤體積的增大(P0.05)、淋巴結(jié)轉(zhuǎn)移(P0.05)和肌層受侵深度的增加(P0.05),血清SCC-Ag值逐步升高,術(shù)后SCC-Ag水平明顯下降(P0.05),且SCC-Ag在髂總淋巴結(jié)轉(zhuǎn)移組表達(dá)水平明顯高于僅盆腔淋巴結(jié)組。而CA125與宮頸鱗狀細(xì)胞癌臨床進(jìn)展無明顯差異(P0.05)。結(jié)論血清SCC-Ag可作為臨床判斷宮頸鱗癌分期及臨床病理特征的重要標(biāo)志物。
[Abstract]:Objective to investigate the correlation between serum squamous cell carcinoma-associated antigen (SCC-Ag) and carbohydrate antigen 125 (CA125) and clinicopathological parameters in squamous cell carcinoma of cervix (SCC). Methods the serum levels of SCC-Ag and CA125 in 338 patients with cervical squamous cell carcinoma in stage 鈪，

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