【摘要】：目的了解妊娠合并急性腎盂腎炎的臨床特點(diǎn),并探討其影響因素。方法以2010年8月—2014年8月在寧波市第一醫(yī)院就診的182例妊娠期急性腎盂腎炎患者為觀察組,以同時(shí)期在該院就診但未合并感染性疾病的164例妊娠期婦女為對(duì)照組。通過查閱電子病歷的方法,收集兩組患者臨床資料,包括年齡、職業(yè)、文化程度、妊娠分期、合并癥、實(shí)驗(yàn)室檢查指標(biāo);同時(shí)收集觀察組患者的臨床表現(xiàn)、超聲檢查結(jié)果、治療與轉(zhuǎn)歸情況。結(jié)果 (1)觀察組182例患者均有畏寒發(fā)熱、寒戰(zhàn)、頭痛、全身酸痛等感染中毒癥狀,伴腰痛的患者數(shù)為135例(占74.2%),無尿路刺激癥狀的患者數(shù)為97例(占53.3%);116例(占63.7%)患者的血紅蛋白(Hb)≤110 g/L;所有患者的尿常規(guī)檢查均呈白細(xì)胞陽性;9例(占4.9%)患者的血培養(yǎng)呈陽性,其中大腸埃希菌6株(占66.7%);41例(占22.5%)患者的尿培養(yǎng)呈陽性,其中大腸埃希菌19株(占46.3%);85例(占46.7%)患者合并腎積水;86例(占47.2%)患者采用頭孢曲松進(jìn)行抗感染治療,完成隨訪的175例患者均治愈。(2)兩組平均年齡、職業(yè)、文化程度、妊娠分期、合并癥、Hb、清蛋白(Alb)比較,差異有統(tǒng)計(jì)學(xué)意義(P0.05);而血肌酐(SCr)和總膽固醇(TC)比較,差異無統(tǒng)計(jì)學(xué)意義(P0.05)。Logistic回歸分析顯示,年齡、妊娠分期、合并癥及Alb對(duì)妊娠合并急性腎盂腎炎的影響有統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論妊娠合并急性腎盂腎炎的起病較急,多伴高熱和腰痛癥狀,半數(shù)以上患者無尿路刺激癥狀,致病菌主要為大腸埃希菌,頭孢曲松等三代頭孢菌素、半合成廣譜青霉素、碳青霉烯類藥物的治療效果較好,治愈率較高。年齡、妊娠分期、合并癥及Alb是妊娠合并急性腎盂腎炎的影響因素。
[Abstract]:Objective to investigate the clinical features of pregnancy complicated with acute pyelonephritis and its influencing factors. Methods 182 patients with acute pyelonephritis of pregnancy were treated in the first Hospital of Ningbo from August 2010 to August 2014, and 164 pregnant women who were not associated with infectious diseases in the same period were taken as the control group. The clinical data including age, occupation, education, pregnancy staging, complications, laboratory examination, clinical manifestations and ultrasonic findings of the two groups were collected by consulting the electronic medical records. Treatment and outcome. Results (1) all the 182 patients in the observation group had symptoms of infection and poisoning, such as chills, headache, general soreness, etc. There were 135 cases (74.2%) with low back pain, 97 cases (53.3%) with no symptoms of urinary tract irritation, 116 cases (63.7%) with hemoglobin (Hb) 鈮，

本文編號(hào)：2269870