【摘要】：目的： 本次研究回顧性分析卵巢上皮性癌患者的一般診療過程，及對(duì)單因素和多因素分析進(jìn)一步探討卵巢上皮性癌的相關(guān)預(yù)后因素。 方法： 收集病例為2006年-2011年于吉林大學(xué)第一醫(yī)院婦科初治的上皮性卵巢癌患者的臨床資料，分析該病臨床特點(diǎn)及發(fā)病年齡、臨床分期、病理類型、手術(shù)方式、術(shù)后化療次數(shù)等與預(yù)后的相關(guān)性。 結(jié)果： 1、236例患者發(fā)病平均年齡52.0歲，發(fā)病高峰年齡為50-59歲，共93例。2、早期患者的臨床表現(xiàn)主要為腹痛癥狀（40.85%）；而晚期患者的臨床表現(xiàn)多集中在消化系統(tǒng)癥狀（69.09%）。3、單因素分析顯示年齡≥50歲，已絕經(jīng)者，妊娠次數(shù)＜3次，生產(chǎn)次數(shù)＜2次，臨床分期晚期、病理類型漿液性、初次術(shù)后殘留病灶大小≥2cm及化療次數(shù)＜6次患者預(yù)后差（P＜0.05）。初潮年齡、組織分化對(duì)預(yù)后無明顯關(guān)系。4、多因素分析顯示妊娠次數(shù)、臨床分期、病理類型、初次術(shù)后殘留病灶大小及化療次數(shù)是影響卵巢上皮性癌的獨(dú)立預(yù)后因素（P＜0.05）。 結(jié)論： 1、50-59歲為卵巢上皮性癌發(fā)病高峰年齡。2、對(duì)于出現(xiàn)腹脹等消化系統(tǒng)癥狀患者及時(shí)進(jìn)行超聲檢查及CA125、HE4等腫瘤標(biāo)志物檢測(cè)，可作為篩查卵巢惡性腫瘤的常規(guī)檢測(cè)手段。3、婦科查體作為腫瘤婦科醫(yī)師必不可少的技能應(yīng)受到充分的重視。4、在行子宮切除時(shí)應(yīng)同時(shí)切除雙側(cè)輸卵管，尤其對(duì)于已完成生育功能且具有卵巢癌家族史的患者應(yīng)切除雙側(cè)輸卵管以降低卵巢癌發(fā)病。5、絕經(jīng)年齡及生產(chǎn)次數(shù)是影響卵巢上皮性癌的危險(xiǎn)因素，，而初潮年齡、組織分化對(duì)預(yù)后無明顯關(guān)系。6、妊娠次數(shù)、臨床分期、病理類型、初次術(shù)后殘留病灶大小及化療次數(shù)可明顯影響卵巢上皮性癌的預(yù)后。
[Abstract]:Objective: to analyze the general diagnosis and treatment process of ovarian epithelial carcinoma and to explore the prognostic factors of ovarian epithelial carcinoma by univariate and multivariate analysis. Methods: the clinical data of patients with epithelial ovarian cancer were collected from 2006 to 2011 in the first Hospital of Jilin University. The correlation between postoperative chemotherapeutic frequency and prognosis. Results: the mean age of 1236 patients was 52.0 years old, the peak age was 50-59 years old, 93 cases were .2.The main clinical manifestations of early patients were abdominal pain (40.85%). The clinical manifestations of the late stage patients were mainly digestive system symptoms (69.09%) .3The univariate analysis showed that the age 鈮

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