重度子癇前期病情發(fā)展與衍變396例分析
發(fā)布時間：2018-09-09 17:37
【摘要】：目的探討重度子癇前期(sPE)患者病情的發(fā)展與衍變,尋求減少疾病發(fā)生、延緩病情發(fā)展及避免嚴重并發(fā)癥和不良結(jié)局的臨床要點。方法分析2009年1月至2012年12月于北京大學第三醫(yī)院住院治療并終止妊娠、在出院時診斷為重度子癇前期的396例患者資料,按入院情況進行分組,包括入院時為單純sPE不伴有嚴重并發(fā)癥(I-sPE)組330例;sPE伴有嚴重并發(fā)癥(C-sPE)組33例;輕度子癇前期(mild preeclampsia)后發(fā)展為sPE(M-sPE)組23例;入院時無子癇前期診斷但住院后發(fā)展成為sPE(N-sPE)組10例。分析指標包括一般臨床資料、產(chǎn)前檢查情況及病情衍變分析。結(jié)果 (1)M-sPE組規(guī)律產(chǎn)檢率最高(87%),C-sPE組規(guī)律產(chǎn)檢率最低(50%)。重癥首診患者中,C-sPE組比例(63.6%)高于I-sPE組(44.2%)(P0.05)。(2)C-sPE組首發(fā)征象出現(xiàn)最早,入院孕周較晚;M-sPE組診斷sPE孕周較晚,分娩孕周均值大于34孕周,無一例出現(xiàn)嚴重并發(fā)癥。(3)N-sPE組10例均存在≥1個的預警信息;8例接受了常規(guī)性的規(guī)律產(chǎn)前檢查;7例臨床首發(fā)征象出現(xiàn)在入院前;入院至sPE診斷中位時間8.0(5.0,16.0)d;sPE診斷至分娩中位時間2.5(0.8,8.5)d。結(jié)論重度子癇前期可以經(jīng)不同發(fā)病情形衍變而來,注重臨床預警信息是早期識別重度子癇前期發(fā)病的重要環(huán)節(jié)之一,在存在子癇前期高危因素的孕婦尤其在期待治療過程中應早期識別、注意防范重度子癇前期發(fā)生;產(chǎn)前檢查和管理質(zhì)量是影響重度子癇前期發(fā)病的重要因素。
[Abstract]:Objective to investigate the development and evolution of (sPE) patients with severe preeclampsia, and to explore the clinical key points to reduce the occurrence of the disease, delay the development of the disease and avoid serious complications and adverse outcomes. Methods from January 2009 to December 2012, the data of 396 patients with severe preeclampsia diagnosed as severe preeclampsia were analyzed. There were 33 cases of sPE with severe complications (C-sPE), 23 cases of sPE (M-sPE) after mild pre-eclampsia (mild preeclampsia), 10 cases of sPE (N-sPE) group with no pre-eclampsia diagnosis at admission. The analysis included general clinical data, prenatal examination and disease evolution analysis. Results (1) M-sPE group had the highest regular rate (87%) and C-sPE group had the lowest regular rate (50%). The proportion of patients with severe first visit in C-sPE group (63.6%) was higher than that in I-sPE group (44.2%) (P0.05). (2). The initial sign of sPE was the earliest in the C-sPE group. The diagnosis of sPE in M-sPE group was later than that in M-sPE group, and the mean gestational week of delivery was more than 34 weeks. No serious complications occurred. (3) in the N-sPE group, 10 cases had 鈮，
本文編號：2233098
[Abstract]:Objective to investigate the development and evolution of (sPE) patients with severe preeclampsia, and to explore the clinical key points to reduce the occurrence of the disease, delay the development of the disease and avoid serious complications and adverse outcomes. Methods from January 2009 to December 2012, the data of 396 patients with severe preeclampsia diagnosed as severe preeclampsia were analyzed. There were 33 cases of sPE with severe complications (C-sPE), 23 cases of sPE (M-sPE) after mild pre-eclampsia (mild preeclampsia), 10 cases of sPE (N-sPE) group with no pre-eclampsia diagnosis at admission. The analysis included general clinical data, prenatal examination and disease evolution analysis. Results (1) M-sPE group had the highest regular rate (87%) and C-sPE group had the lowest regular rate (50%). The proportion of patients with severe first visit in C-sPE group (63.6%) was higher than that in I-sPE group (44.2%) (P0.05). (2). The initial sign of sPE was the earliest in the C-sPE group. The diagnosis of sPE in M-sPE group was later than that in M-sPE group, and the mean gestational week of delivery was more than 34 weeks. No serious complications occurred. (3) in the N-sPE group, 10 cases had 鈮，
本文編號：2233098
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