【摘要】：目的:分析卵巢交界性腫瘤(BOT)患者的臨床特征、手術(shù)方式及預(yù)后等情況,以指導(dǎo)臨床醫(yī)生對不同患者選擇最佳治療方案。方法:對2012年1月1日至2015年12月31日期間蚌醫(yī)一附院的卵巢交界性腫瘤患者行回顧性分析。比較其臨床特點(diǎn)、病理類型、輔助檢查、臨床分期、手術(shù)方式及術(shù)后治療情況,并分析其預(yù)后。所有病例信息來源于我院病案室、病理科及彩超室。結(jié)果:共有72例患者納入分析。其年齡中位數(shù)為44歲(范圍18~85歲),平均年齡45.21±16.19歲。大多數(shù)的患者(84.7%)表現(xiàn)為國際婦產(chǎn)科聯(lián)盟(FIGO)分期I期,其余為FIGO分期II/III期(II期4.2%,III期11.1%)。這些患者中,漿液性腫瘤占58.3%,粘液性為37.5%,其余為子宮內(nèi)膜樣和混合型。其中血清癌抗原125(CA125)水平升高發(fā)生于54.2%的患者中。所有患者均接受手術(shù)治療,行保留生育功能的手術(shù)者占44.4%,根治性手術(shù)者為55.6%(40/72),有3例患者行雙附件+大網(wǎng)膜切除術(shù),歸為根治性手術(shù)。Ⅰ期患者行保留生育功能手術(shù)的復(fù)發(fā)率顯著高于根治性手術(shù)者(P0.05)。腫瘤剝除比患側(cè)附件切除者更容易復(fù)發(fā)。所有患者有6.9%行輔助化療。術(shù)后隨訪10~55月,僅1例出現(xiàn)腫瘤相關(guān)性死亡,11.1%出現(xiàn)復(fù)發(fā)。復(fù)發(fā)后部分行手術(shù)治療,其中有1例局部癌變。結(jié)論:BOT預(yù)后良好,臨床表現(xiàn)無明顯特異性,手術(shù)是其主要治療方法。育齡期有生殖意愿的患者可行保留生育功能的手術(shù),Ⅰ期者建議行患側(cè)附件切除術(shù)。對于行保留生育功能手術(shù)的患者應(yīng)行長期密切隨訪。無生育要求者建議行根治性手術(shù)。術(shù)后輔助化療對BOT的作用不大,不建議行輔助化療。
[Abstract]:Objective: to analyze the clinical features, surgical methods and prognosis of (BOT) patients with borderline ovarian tumors, so as to guide clinicians to choose the best treatment for different patients. Methods: the patients with borderline ovarian tumors from January 1, 2012 to December 31, 2015 were retrospectively analyzed. The clinical features, pathological types, adjuvant examinations, clinical stages, surgical procedures and postoperative treatment were compared and their prognosis was analyzed. All cases were collected from the medical records room, pathology department and color Doppler room of our hospital. Results: a total of 72 patients were included in the analysis. The median age was 44 years (range 18 to 85 years), with an average age of 45.21 鹵16.19 years. The majority of the patients (84.7%) showed stage I of (FIGO) in the International Federation of Obstetrics and Gynaecology, and the rest of the patients were in II/III stage of FIGO stage (II 4.2%, stage III 11.1%). Of these patients, serous tumors accounted for 58.3 percent, mucus 37.5 and endometrioid and mixed. The serum CA125 level increased in 54.2% of the patients. All the patients received surgical treatment. 44.4% of the patients underwent surgery and 55.6% (40 / 72) of the patients underwent radical surgery. Three patients underwent double adnexal omentectomy. The recurrence rate of stage 鈪，

本文編號：2222508