卵母細(xì)胞玻璃化冷凍的臨床結(jié)局分析
[Abstract]:Objective to investigate the clinical outcome of in vitro fertilization and embryo transfer after vitrification and thawing of oocytes. Methods from January 2010 to October 2014, the resuscitation rate and 2PN fertilization rate of 68 infertile oocytes from the Reproductive Medicine Center of the third Hospital of Peking University after vitrification and thawing for in vitro fertilization and embryo transfer (in vitro fertilization-embryo transfer,IVF-ET) were analyzed retrospectively. Embryo implantation rate, abortion rate and delivery rate, and other clinical outcomes. Results there were 756 oocytes in thawed vitrification, and the recovery rate was 80.69% (610 / 756). The fertilization rate of 519 MII oocytes was 53.56% (278 / 519). There was no embryogenesis in 12 of 68 patients, accounting for 17.65.56 of them, the fresh embryos were transferred for 51 cycles. Thawed embryos were transferred for 15 cycles. The clinical pregnancy rate of 51 cycles of fresh embryo transfer was 54.90% (28 / 51), and the delivery rate of live fetus was 45.10% (23 / 51). The clinical pregnancy rate was 60.00% (9 / 15) and the delivery rate of live fetus was 46.67% (7 / 15) in 15 cycles of thawed embryo transfer. The cumulative pregnancy rate was 55.88% (38 / 68). The rate of delivery of live fetus per thawed oocyte was 5.03% (38 / 756). Conclusion vitrified cryopreservation of oocytes can obtain good pregnancy outcome in patients who can not obtain sperm on the day of oocyte collection.
【作者單位】: 北京大學(xué)第三醫(yī)院生殖醫(yī)學(xué)中心;
【基金】:首都衛(wèi)生發(fā)展科研專(zhuān)項(xiàng)項(xiàng)目(首發(fā)2014-1-4091)
【分類(lèi)號(hào)】:R714.8
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