卵巢轉(zhuǎn)移性黏液性腫瘤27例臨床病理分析
發(fā)布時間：2018-07-26 14:26
【摘要】：目的探討卵巢轉(zhuǎn)移性黏液性腫瘤(metastatic mucinous neoplasms,MMN)的臨床病理學特征。方法對27例卵巢MMN標本行HE、免疫組化SP法染色及臨床病理資料分析。結(jié)果 27例卵巢MMN腫瘤直徑2~28 cm,平均12.5 cm;發(fā)生于雙側(cè)者12例,單側(cè)者15例(右側(cè)13例);來源于闌尾19例、結(jié)腸5例、子宮頸2例、胰腺1例;大體呈囊性或囊實性者16例,實性11例;光鏡下來源于闌尾及胰腺者可見類似良性的囊腺瘤樣區(qū)域,實性區(qū)域可見毀損性的間質(zhì)浸潤,來源于結(jié)腸及子宮頸者可見彌漫性間質(zhì)浸潤及黏液滲出;免疫組化標記CK20多數(shù)陽性,CK7少數(shù)陽性,MUC-2的陽性率高于MUC-1,CDX-2及villin絕大多數(shù)陽性。結(jié)論卵巢MMN的診斷需緊密聯(lián)系臨床,免疫組化標記僅有一定的輔助作用。
[Abstract]:Objective to investigate the clinicopathological features of ovarian metastatic mucinous tumor (metastatic mucinous neoplasm). Methods 27 cases of ovarian MMN were studied by immunohistochemistry SP staining and clinicopathological data. Results 27 cases of ovarian MMN tumors were 28 cm in diameter (mean 12.5 cm), bilateral in 12 cases, unilateral in 15 cases (right 13 cases), originated from appendix in 19 cases, colon in 5 cases, cervix in 2 cases, pancreas in 1 case, cystic or cystic in 16 cases. 11 cases were solid. Diffuse interstitial infiltration and mucus exudation could be seen in the solid area and colon and cervix in 11 cases which were similar to benign cystadenomatous area under the light microscope, and diffuse interstitial infiltration and mucus exudation could be seen in the solid area from the colon and cervix. Immunohistochemical staining showed that the majority of CK20 positive and a few of Muc-2 positive were higher than those of MUC-1, CDX-2 and villin. Conclusion the diagnosis of ovarian MMN should be closely related to clinic.
【作者單位】： 安徽醫(yī)科大學基礎醫(yī)學院病理學教研室;安徽省立醫(yī)院病理科;
【基金】：安徽省衛(wèi)生廳醫(yī)學科研課題(13zc037)
【分類號】：R737.31
[Abstract]:Objective to investigate the clinicopathological features of ovarian metastatic mucinous tumor (metastatic mucinous neoplasm). Methods 27 cases of ovarian MMN were studied by immunohistochemistry SP staining and clinicopathological data. Results 27 cases of ovarian MMN tumors were 28 cm in diameter (mean 12.5 cm), bilateral in 12 cases, unilateral in 15 cases (right 13 cases), originated from appendix in 19 cases, colon in 5 cases, cervix in 2 cases, pancreas in 1 case, cystic or cystic in 16 cases. 11 cases were solid. Diffuse interstitial infiltration and mucus exudation could be seen in the solid area and colon and cervix in 11 cases which were similar to benign cystadenomatous area under the light microscope, and diffuse interstitial infiltration and mucus exudation could be seen in the solid area from the colon and cervix. Immunohistochemical staining showed that the majority of CK20 positive and a few of Muc-2 positive were higher than those of MUC-1, CDX-2 and villin. Conclusion the diagnosis of ovarian MMN should be closely related to clinic.
【作者單位】： 安徽醫(yī)科大學基礎醫(yī)學院病理學教研室;安徽省立醫(yī)院病理科;
【基金】：安徽省衛(wèi)生廳醫(yī)學科研課題(13zc037)
【分類號】：R737.31
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