【摘要】：目的 研究單、雙側(cè)卵巢切除對(duì)圍絕經(jīng)期女性生活質(zhì)量的影響。方法 選取婦產(chǎn)科進(jìn)行單、雙側(cè)卵巢切除術(shù)的圍絕經(jīng)期患者90例,其中單側(cè)45例,雙側(cè)45例,比較兩組受試者的FSH、LH、E2水平、骨密度變化及其絕經(jīng)相關(guān)癥狀。結(jié)果 單側(cè)組后3、6個(gè)月FSH、LH升高,E2下降與術(shù)前比較差異有統(tǒng)計(jì)學(xué)意義(P0.05),雙側(cè)組術(shù)后3、6、12個(gè)月FSH、LH升高,E2下降,與術(shù)前比較,差異有統(tǒng)計(jì)學(xué)意義(P0.05)。在術(shù)后3、6、12個(gè)月,兩組的骨密度與術(shù)前相比,均沒(méi)有顯著變化(P0.05)。術(shù)后3、6、12個(gè)月,雙側(cè)組患者的絕經(jīng)相關(guān)癥狀均顯著高于單側(cè)組,差異有統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論 雙側(cè)卵巢切除與單側(cè)卵巢切除術(shù)比較,婦女術(shù)后體內(nèi)激素水平急驟改變,對(duì)患者的生活質(zhì)量影響更嚴(yán)重,應(yīng)該盡可能的保存卵巢的功能。
[Abstract]:Objective to study the effect of unilateral and bilateral ovariectomy on the quality of life of menopausal women. Methods 90 cases of perimenopausal women undergoing single and bilateral ovariectomy were selected, including 45 cases of unilateral and 45 cases of bilateral. The level of FSHLHN E2, the changes of bone mineral density and menopausal symptoms were compared between the two groups. Results in the unilateral group, the level of FSH LH increased and decreased significantly at the 3rd and 6th month after operation (P0.05), while in the bilateral group, the level of FSHLH increased at 6 and 12 months after operation, and there was a significant difference between the two groups (P0.05). There was no significant change in bone mineral density (BMD) between the two groups at 3 and 12 months postoperatively (P0.05). The menopausal symptoms in the bilateral group were significantly higher than those in the unilateral group at 3 and 12 months postoperatively (P0.05). Conclusion compared with unilateral ovariectomy, the changes of hormone level in women after operation are more serious to the quality of life, and the function of ovary should be preserved as much as possible.
【作者單位】： 北京市順義區(qū)醫(yī)院婦產(chǎn)科;

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