【摘要】：目的：探討女性卵巢惡性腫瘤的臨床特征、具體病理分型、手術(shù)實(shí)施方案、術(shù)后化療方案以及生殖功能的保留對預(yù)后的影響。研究方法：對江蘇省連云港市婦幼保健院2003-2013年10年間收治的患有卵巢惡性腫瘤的女性患者的病案進(jìn)行回顧性的分析和總結(jié)。系統(tǒng)整理其臨床特征、具體病理分型、疾病的臨床分期、不同的手術(shù)方案、術(shù)后進(jìn)行輔助化療的差異、術(shù)后的生殖功能保留情況及預(yù)后，運(yùn)用SPSS16.0軟件進(jìn)行統(tǒng)計(jì)分析，P0.05表示存在顯著性差異。結(jié)果：10年間江蘇省連云港市婦幼保健院共收治卵巢惡性腫瘤患者54例，最小年齡16歲，最大年齡67歲，，平均年齡31.2歲，中位年齡24.6歲。其中交界性上皮性腫瘤患者7例，卵巢上皮性惡性腫瘤患者15例，卵巢性索間質(zhì)性腫瘤患者5例，生殖細(xì)胞性腫瘤患者20例，轉(zhuǎn)移性腫瘤患者7例�；颊邿o特異性臨床表現(xiàn)，腹痛、腹脹、腹部包塊是患者的通常表現(xiàn)，少數(shù)存在與月經(jīng)相關(guān)的臨床癥狀。患者多數(shù)為較早的臨床分期， I期患者為26例，占48%；Ⅱ期患者6例，占11%；Ⅲ期患者13例，占24%；Ⅳ期患者9例，占16%。卵巢惡性腫瘤的預(yù)后情況和其臨床分期直接相關(guān)，患者的預(yù)后情況的主要影響因素就是其臨床分期。結(jié)論：生殖細(xì)胞腫瘤是卵巢惡性腫瘤最重要的一類。卵巢惡性腫瘤缺乏特異性的臨床表現(xiàn)，而且早期篩查手段也不具備，因此對于女性婦科影像學(xué)檢查也加以重視�；加新殉矏盒阅[瘤的年紀(jì)較輕的女性患者，不管分期如何，其生育功能都可以保留，提高其生存質(zhì)量。但是后期的隨訪非常必要。對于處于I期、 Ⅱ期的上皮性惡性腫瘤患者，患者有生育要求的，在長期嚴(yán)密隨訪的情況下，生育功能也可以保留。在本研究中，I期、 Ⅱ期上皮性惡性腫瘤患者中，不乏成功妊娠的案例，但是臨床樣本量還不夠大。對于女性患者而言，一些能夠盡量將卵巢以及生殖功能保留的保守治療方案在臨床上意義重大。卵巢惡性腫瘤在術(shù)后所進(jìn)行的化療會(huì)對卵巢功能產(chǎn)生一過性的影響。對于患有婦科惡性腫瘤的年輕女性，應(yīng)該根據(jù)患者自身情況，制定個(gè)性化的治療方案，不但要考慮到保守手術(shù)所存在的風(fēng)險(xiǎn)，還要考慮到根治手術(shù)所存在的缺陷，在兩者之間找到平衡點(diǎn)。
[Abstract]:Objective: to investigate the effect of clinical features, pathological classification, operative regimen, postoperative chemotherapy and reproductive function retention on the prognosis of female ovarian malignant tumors. Methods: the medical records of female patients with ovarian malignant tumor admitted from 2003 to 2013 in Lianyungang MCH Hospital of Jiangsu Province were retrospectively analyzed and summarized. The clinical features, specific pathological types, clinical stages of the disease, different surgical schemes, differences in postoperative adjuvant chemotherapy, preservation of reproductive function and prognosis were systematically sorted out. SPSS 16.0 software was used for statistical analysis. Results during the past 10 years, 54 patients with malignant ovarian tumors were treated in Lianyungang MCH Hospital of Jiangsu Province. The youngest age was 16 years, the maximum age was 67 years, the average age was 31.2 years, and the median age was 24.6 years. Among them, there were 7 cases of borderline epithelial tumor, 15 cases of ovarian epithelial malignant tumor, 5 cases of ovarian cord stromal tumor, 20 cases of germ cell tumor and 7 cases of metastatic tumor. No specific clinical manifestations, abdominal pain, abdominal distension, abdominal mass is the usual manifestation of patients, a few clinical symptoms associated with menstruation. The majority of the patients were early clinical staging, with 26 patients in stage I (48 patients), 6 patients in stage II (1111patients), 13 patients in stage 鈪

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