本文選題：宮頸上皮內瘤變 + 高危型人乳頭瘤病毒�。� 參考：《實用醫(yī)學雜志》2015年04期

【摘要】：目的:探討高危型人乳頭瘤病毒(HR-HPV)檢測在宮頸錐切術(Cold Knife Conization,CKC)術后隨訪的臨床應用價值。方法:將行宮頸錐形切除術的205例患者為隨訪對象,根據病理結果分為2組:未累腺組(92例)及累腺組(113例),對其手術前后的HPV感染變化情況進行觀察及分析。結果:兩組患者術后HPV轉陰率相比差異無統計學意義(P0.05);是否累及腺體及HPV負荷量是CKC術后殘存病變或復發(fā)的危險因素(P0.05);HPV負荷量1 000的宮頸錐切術后患者的殘存病變或復發(fā)的危險性是HPV負荷量≤500的7.286倍。結論:累腺患者術后殘存病變或復發(fā)的危險性更高;HPV負荷量越高,術后殘存病變或復發(fā)的機率越大;HPV檢測能幫助預測CIN宮頸錐切術后的復發(fā)率。
[Abstract]:Objective: to evaluate the clinical value of high risk human papillomavirus (HR-HPV) detection in the follow-up of cervical conization (Cold Knife conization CKC). Methods: 205 cases of cervical conical resection were followed up. According to the pathological results, 205 patients were divided into two groups: unaffected gland group (92 cases) and involved gland group (113 cases). The changes of HPV infection before and after operation were observed and analyzed. Results: there was no significant difference in HPV negative rate between the two groups (P0.05), and the risk factor of residual lesion or recurrence after CKC was whether the HPV load was involved or not (P0.05). The risk of change or recurrence was 7.286 times greater than that of HPV load 鈮，

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