本文選題：宮頸上皮內(nèi)瘤變 + 高危型人乳頭瘤病毒��； 參考：《實(shí)用醫(yī)學(xué)雜志》2015年04期

【摘要】：目的:探討高危型人乳頭瘤病毒(HR-HPV)檢測(cè)在宮頸錐切術(shù)(Cold Knife Conization,CKC)術(shù)后隨訪的臨床應(yīng)用價(jià)值。方法:將行宮頸錐形切除術(shù)的205例患者為隨訪對(duì)象,根據(jù)病理結(jié)果分為2組:未累腺組(92例)及累腺組(113例),對(duì)其手術(shù)前后的HPV感染變化情況進(jìn)行觀察及分析。結(jié)果:兩組患者術(shù)后HPV轉(zhuǎn)陰率相比差異無(wú)統(tǒng)計(jì)學(xué)意義(P0.05);是否累及腺體及HPV負(fù)荷量是CKC術(shù)后殘存病變或復(fù)發(fā)的危險(xiǎn)因素(P0.05);HPV負(fù)荷量1 000的宮頸錐切術(shù)后患者的殘存病變或復(fù)發(fā)的危險(xiǎn)性是HPV負(fù)荷量≤500的7.286倍。結(jié)論:累腺患者術(shù)后殘存病變或復(fù)發(fā)的危險(xiǎn)性更高;HPV負(fù)荷量越高,術(shù)后殘存病變或復(fù)發(fā)的機(jī)率越大;HPV檢測(cè)能幫助預(yù)測(cè)CIN宮頸錐切術(shù)后的復(fù)發(fā)率。
[Abstract]:Objective: to evaluate the clinical value of high risk human papillomavirus (HR-HPV) detection in the follow-up of cervical conization (Cold Knife conization CKC). Methods: 205 cases of cervical conical resection were followed up. According to the pathological results, 205 patients were divided into two groups: unaffected gland group (92 cases) and involved gland group (113 cases). The changes of HPV infection before and after operation were observed and analyzed. Results: there was no significant difference in HPV negative rate between the two groups (P0.05), and the risk factor of residual lesion or recurrence after CKC was whether the HPV load was involved or not (P0.05). The risk of change or recurrence was 7.286 times greater than that of HPV load 鈮，

本文編號(hào)：2114854