本文選題：ω-脂肪酸 + 糖尿病　； 參考：《現(xiàn)代預(yù)防醫(yī)學》2015年12期

【摘要】：目的探究妊娠期糖尿病孕婦空腹血清ω-3脂肪酸水平對胰島素抵抗的影響。方法測定40例妊娠期糖尿病孕婦(GDM組)、40例正常妊娠孕婦(正常妊娠組)空腹血清ω-3脂肪酸、胰島素、血糖、糖化血紅蛋白(Hb A1c)水平;并計算2組孕婦胰島素抵抗指數(shù)(Insulin Resistance IRI)。結(jié)果 GDM組孕婦空腹血清ω-3脂肪酸水平較正常妊娠組明顯減少,2組比較差異有統(tǒng)計學意義(t=26.78,P0.05);GDM組孕婦IRI、空腹血糖、胰島素、Hb A1c水平明顯高于正常妊娠組,2組比較差異有統(tǒng)計學意義(t=32.56,t=18.25,t=15.31,t=13.24,P0.05)。(2)GDM組孕婦血清ω-3脂肪酸水平與IRI、空腹血糖、Hb A1c呈負相關(guān)(r=-0.812,r=-0.545,r=-0.296,P0.05),與胰島素水平無相關(guān)性(r=0.197,P0.05)。正常妊娠組孕婦血清ω-3脂肪酸與IRI呈負相關(guān),(r=-0.280,P0.05),相關(guān)性小于GDM組,正常妊娠組孕婦ω-3脂肪酸水平與胰島素、血糖、Hb A1c無相關(guān)性(r=0.213、0.179、0.195)。結(jié)論提高GDM孕婦血清ω-3脂肪酸含量可減輕其胰島素抵抗的程度。
[Abstract]:Objective to investigate the effect of fasting serum omega-3 fatty acid level on insulin resistance in pregnant women with gestational diabetes mellitus. Methods the fasting serum levels of omega-3 fatty acid, insulin, blood glucose and HbA1c were measured in 40 pregnant women with gestational diabetes mellitus (GDM group) and 40 normal pregnant women (normal pregnancy group), and the insulin resistance IRI was calculated. Results the fasting serum omega-3 fatty acid level in GDM group was significantly lower than that in normal pregnancy group. The level of serum omega-3 fatty acid in GDM group was significantly higher than that in normal pregnancy group (P 0.05). There was a negative correlation between serum omega-3 fatty acid level and IRI, fasting blood glucose level and HbA1c level (r -0.812r-0.545r-0.296p 0.05), but no correlation with insulin level (r 0.197). There was a negative correlation between serum 蠅 -3 fatty acids and IRI in normal pregnancy group (r = 0.280), which was lower than that in GDM group. There was no correlation between omega-3 fatty acid level and insulin and blood glucose HbA1c in normal pregnant women (r = 0.213 鹵0.179 鹵0.195). Conclusion increasing the content of omega-3 fatty acids in serum of GDM pregnant women can reduce the degree of insulin resistance.
【作者單位】： 石河子大學第一附屬醫(yī)院婦產(chǎn)科;
【基金】：科技部國家級科技惠民計劃(2013GS650104)
【分類號】：R714.256

【參考文獻】

相關(guān)期刊論文 前3條

1 周鋒;張培趁;余震;章曉東;余作黔;姚建高;;ω-3多不飽和脂肪酸對胃癌病人術(shù)后炎性反應(yīng)和疲勞綜合征的影響[J];腸外與腸內(nèi)營養(yǎng);2012年01期

2 陳慧;;個體化營養(yǎng)膳食治療妊娠期糖尿病的臨床療效[J];現(xiàn)代預(yù)防醫(yī)學;2012年11期

3 陳霞;;個性化健康教育在妊娠期糖尿病患者中的臨床應(yīng)用[J];現(xiàn)代預(yù)防醫(yī)學;2012年21期

【共引文獻】

相關(guān)期刊論文 前10條

1 陳滿;汪志紅;張力;張軍;李啟富;劉智平;唐瑤;陳書梅;劉秀容;楊淑敏;;腹腔鏡下Roux-en-Y胃旁路術(shù)治療肥胖2型糖尿病患者的近期療效分析[J];第三軍醫(yī)大學學報;2014年07期

2 吳天添;朱江;毛翔宇;張昌靜;莊成樂;陳偉哲;劉舒;余震;;亮氨酸對腸道術(shù)后大鼠中樞神經(jīng)遞質(zhì)和外周炎性因子的影響[J];腸外與腸內(nèi)營養(yǎng);2014年03期

3 李柯;史蕾U，

本文編號：2111165