本文選題：多囊卵巢綜合征 + 肥胖�。� 參考：《安徽醫(yī)科大學學報》2015年04期

【摘要】：目的探討多囊卵巢綜合征(PCOS)患者的臨床特點和發(fā)病機制。方法收集219例符合2003年鹿特丹診斷標準的PCOS患者,同時選取63例正常者作為對照組(N組);將PCOS患者分為兩組:體重正常的PCOS患者為LP組,超重或肥胖的PCOS患者為NLP組。采集病史,進行體格檢查;測定性激素及血糖、血脂等各項生化指標,進行口服糖耐量試驗;最后對數(shù)據(jù)進行統(tǒng)計學分析。結(jié)果 1 219例PCOS患者里存在胰島素抵抗(IR)患者[胰島素抵抗指數(shù)(HOMA-IR)≥2.69]144例(66.36%)。2 NLP組空腹、餐后胰島素水平升高,與N組相比差異有統(tǒng)計學意義(P0.01);3 LP組促黃體生成素(LH)、睪酮(T)與N組相比增高,差異有統(tǒng)計學意義(P0.05,P0.01)。結(jié)論 IR不是PCOS發(fā)病的單純因素,卵巢功能異常亦需關(guān)注。
[Abstract]:Objective to investigate the clinical features and pathogenesis of polycystic ovary syndrome (PCOS). Methods 219 PCOS patients who met the Rotterdam diagnostic criteria in 2003 and 63 normal subjects as control group were divided into two groups: LP group with normal body weight and NLP group with overweight or obese PCOS patients. Collection of medical history, physical examination; determination of sex hormones, blood sugar, blood lipid and other biochemical indicators, oral glucose tolerance test; finally, statistical analysis of the data. Results in 1,219 PCOS patients with insulin resistance (IR) [HOMA-IR 鈮，

本文編號：2092052