發(fā)布時(shí)間：2018-06-21 19:34

  本文選題：高效價(jià)聯(lián)合抗反轉(zhuǎn)錄病毒治療 + 孕期增重��； 參考：《廣東醫(yī)學(xué)》2017年22期

【摘要】：目的研究接受高效價(jià)聯(lián)合抗反轉(zhuǎn)錄病毒療法(HAART)治療的艾滋病病毒(HIV)感染孕婦的營養(yǎng)狀況與不良出生結(jié)局之間的關(guān)系。方法通過對接受正規(guī)治療并定期產(chǎn)檢的HIV感染孕婦跟蹤研究首次產(chǎn)檢和孕期體重及體質(zhì)指數(shù)、孕期增重、新生兒出生體重、身長等多項(xiàng)指標(biāo),描述接受HAART治療的HIV感染孕婦的基礎(chǔ)營養(yǎng)狀況,分析孕婦的營養(yǎng)狀況和不良出生結(jié)局之間的關(guān)系。結(jié)果共有55例孕婦完成調(diào)查隨訪,孕婦孕期體重增加2~20 kg,平均增重(10.35±3.98)kg。分娩孕周31~39+6周,新生兒體重1.8~3.95 kg,平均(2.8±0.47)kg,新生兒評分8~10分,無窒息兒出生。出生低體重兒12例(21.8%),胎兒生長受限7例(12.7%),早產(chǎn)7例(12.7%)。孕期增重不足組33例,占60%,其新生兒體重、身長、頭圍值顯著低于孕期增重正常組,差異有統(tǒng)計(jì)學(xué)意義(P0.05,P0.01),且低出生體重發(fā)生率顯著高于孕期增重正常組(P0.05)。Pearson簡單相關(guān)分析表明,孕期增重與新生兒體重呈顯著正相關(guān)(r=0.549,P0.01)。結(jié)論接受HAART治療的HIV感染孕婦營養(yǎng)狀況一般,孕期體重增加明顯不足,出生低體重兒發(fā)生率高,孕期增重不足與新生兒出生低體重相關(guān)。
[Abstract]:Objective to study the relationship between nutritional status and adverse birth outcomes of HIV-infected pregnant women treated with high titer combined with antiretroviral therapy (HAART). Methods the pregnant women with HIV infection who received regular treatment and regular birth examination were followed up to study such indexes as body weight and body mass index, weight gain during pregnancy, birth weight of newborn, length of body, etc. The basic nutritional status of HIV-infected pregnant women treated with HAART was described and the relationship between nutritional status and poor birth outcome was analyzed. Results A total of 55 pregnant women were followed up. The pregnant women gained 20 kg weight and 10.35 鹵3.98 kg weight gain during pregnancy. The newborn weight was 1.8 鹵3.95 kg (mean 2.8 鹵0.47 kg), the neonatal score was 810 ~ 10, and the unasphyxiated infant was born. There were 12 cases of low birth weight infants, 7 cases of fetal growth restriction, 7 cases of premature birth and 7 cases of premature birth. There were 33 cases (60%) with insufficient weight gain during pregnancy. The neonatal weight, body length and head circumference value were significantly lower than those of normal weight gain group during pregnancy. The difference was statistically significant (P 0.05), and the incidence of low birth weight was significantly higher than that of normal weight gain group during pregnancy (P 0.05N. Pearson). There was a significant positive correlation between weight gain during pregnancy and neonatal body weight. Conclusion the nutritional status of HIV-infected pregnant women treated with HAART is general, the weight gain during pregnancy is obviously insufficient, the incidence of low birth weight infants is high, and the insufficient weight gain during pregnancy is related to the low birth weight of newborns.
【作者單位】： 廣州市第八人民醫(yī)院婦產(chǎn)科;廣州市第八人民醫(yī)院感染科;
【基金】：廣東省科技計(jì)劃項(xiàng)目(編號:2013B021800053)
【分類號】：R714.251

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